Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 3/20 | 0.47 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GPR3 | P46089 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MC4R | P32245 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4550825 | 0.88 | HTT (0.49) | CYP2C9CYP17A1CYP2C19ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL2714321 | 0.87 | LMNA (0.47) | CYP2C9CYP17A1CYP2C19ALDH1A1MAPT | |
| SCHEMBL26100040 | 0.83 | CYP2C9 (0.48) | CYP2C9CYP17A1CYP2C19ALDH1A1MAPT | |
| SCHEMBL26099525 | 0.81 | ADRA2A (0.50) | CYP2C9CYP17A1CYP2C19ALDH1A1MAPT | |
| SCHEMBL16089009 | 0.80 | CYP2C9 (0.48) | CYP2C9CYP17A1CYP2C19ALDH1A1MAPT | |
| SCHEMBL10290354 | 0.77 | CYP2C9 (0.45) | CYP2C9CYP17A1CYP2C19ALDH1A1MAPT | |
| SCHEMBL23977881 | 0.76 | MCL1 (0.54) | CYP2C9CYP17A1CYP2C19ALDH1A1MAPT | |
| SCHEMBL14120796 | 0.74 | PDE2A (0.54) | ALDH1A1KMT2AMEN1HTTCYP1A2 | |
| SCHEMBL2691207 | 0.74 | CYP2C9 (0.54) | CYP2C9CYP17A1CYP2C19ALDH1A1MAPT | |
| SCHEMBL26099687 | 0.73 | MAPT (0.41) | CYP2C9CYP17A1CYP2C19ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230136562-A1 | SPIROUREA DERIVATIVES | IDORSIA PHARMACEUTICALS LTD (CH) | 2023-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230136562-A1 | SPIROUREA DERIVATIVES | KCNA7, PKD2, KCNN3 | CYP2C9 661/4885CYP17A1 883/4885CYP2C19 842/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.