Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 3/20 | 0.48 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GPR3 | P46089 | 1/20 | 0.39 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | G6PD | P11413 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16089009 | 0.88 | CYP2C9 (0.48) | CYP2C9CYP17A1CYP2C19ALDH1A1MAPT | |
| SCHEMBL28408064 | 0.83 | NQO1 (0.45) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL26099839 | 0.83 | CYP2C9 (0.47) | CYP2C9CYP17A1CYP2C19ALDH1A1MAPT | |
| SCHEMBL26099525 | 0.82 | ADRA2A (0.50) | CYP2C9CYP17A1CYP2C19ALDH1A1MAPT | |
| SCHEMBL4550825 | 0.80 | HTT (0.49) | CYP2C9CYP17A1CYP2C19ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL2714321 | 0.79 | LMNA (0.47) | CYP2C9CYP17A1CYP2C19ALDH1A1MAPT | |
| SCHEMBL28567509 | 0.79 | PDE2A (0.49) | CYP2C9CYP1A2GPR3LMNAUSP2 | |
| SCHEMBL20472376 | 0.79 | PDE2A (0.49) | CYP2C9CYP1A2GPR3LMNAUSP2 | |
| SCHEMBL21199382 | 0.79 | PDE2A (0.49) | CYP2C9CYP1A2GPR3LMNAUSP2 | |
| SCHEMBL30468376 | 0.79 | PDE2A (0.49) | CYP2C9CYP1A2GPR3LMNAUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230136562-A1 | SPIROUREA DERIVATIVES | IDORSIA PHARMACEUTICALS LTD (CH) | 2023-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230136562-A1 | SPIROUREA DERIVATIVES | KCNA7, PKD2, KCNN3 | CYP2C9 661/4885CYP17A1 883/4885CYP2C19 842/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.