Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 7/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | CIT | O14578 | 1/20 | 0.35 |
| ▸ | PRKCB | P05771 | 1/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.35 |
| ▸ | MYLK2 | Q9H1R3 | 1/20 | 0.35 |
| ▸ | BMP2K | Q9NSY1 | 1/20 | 0.35 |
| ▸ | AURKC | Q9UQB9 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15491236 | 0.89 | UHRF1 (0.48) | UHRF1HDAC4HDAC1HDAC6DYRK1A | |
| SCHEMBL30490644 | 0.84 | UHRF1 (0.52) | UHRF1HDAC4HDAC1HDAC6DYRK1A | |
| SCHEMBL84469 | 0.84 | UHRF1 (0.52) | UHRF1HDAC4HDAC1HDAC6DYRK1A | |
| SCHEMBL17000190 | 0.80 | UHRF1 (0.48) | UHRF1HDAC4HDAC1HDAC6DYRK1A | |
| SCHEMBL20508491 | 0.80 | UHRF1 (0.48) | UHRF1HDAC4HDAC1HDAC6DYRK1A | |
| SCHEMBL19846691 | 0.80 | UHRF1 (0.48) | UHRF1HDAC4HDAC1HDAC6DYRK1A | |
| SCHEMBL4327140 | 0.80 | UHRF1 (0.48) | UHRF1HDAC4HDAC1HDAC6DYRK1A | |
| SCHEMBL21762132 | 0.80 | UHRF1 (0.48) | UHRF1HDAC4HDAC1HDAC6DYRK1A | |
| SCHEMBL17198732 | 0.80 | UHRF1 (0.48) | UHRF1HDAC4HDAC1HDAC6DYRK1A | |
| SCHEMBL28234404 | 0.80 | UHRF1 (0.48) | UHRF1HDAC4HDAC1HDAC6DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11780861-B2 | Phosphine reagents for azine fluoroalkylation | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2023-10-10 | — | — | US | disclosed |
| EP-3889150-A1 | COMPOUND SERVING AS IRAK INHIBITOR | Shanghai Meiyue Biotech Development Co., Ltd. (CN) | 2021-10-06 | — | — | EP | disclosed |
| US-20200390100-A1 | SUBSTITUTED N-HETEROCYCLYL- AND N-HETEROARYL-TETRAHYDROPYRIMIDINONES AND THE SALTS THEREOF, AND THE USE OF SAME AS HERBICIDAL ACTIVE SUBSTANCES | BAYER AG (DE) | 2020-12-17 | — | — | US | disclosed |
| WO-2018114596-A1 | SUBSTITUTED HETEROARYL PYRROLONES AND SALTS THEREOF AND USE THEREOF AS HERBICIDAL ACTIVE SUBSTANCES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-06-28 | — | — | WO | disclosed |
| EP-2941426-B1 | SUBSTITUTED PYRIMIDINE AMINOALKYL-QUINAZOLONES AS PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | GILEAD CALISTOGA LLC (US) | 2018-06-13 | — | — | EP | disclosed |
| US-9738634-B2 | Heterocyclic amide compound and herbicide | SYNGENTA PARTICIPATIONS AG (CH) | 2017-08-22 | — | — | US | disclosed |
| EP-2938344-B1 | PIPERAZINE-SUBSTITUTED [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINE COMPOUNDS WITH A2A ANTAGONIST PROPERTIES | MERCK SHARP & DOHME (US) | 2017-06-21 | — | — | EP | disclosed |
| US-9676780-B2 | Piperazine-substituted [1,2,4]triazolo[1,5-C]quinazolin-5-amine compounds with A2A antagonist properties | MERCK SHARP & DOHME CORP. (US) | 2017-06-13 | — | — | US | disclosed |
| US-20160221998-A1 | HETEROCYCLIC AMIDE COMPOUND AND HERBICIDE | SYNGENTA PARTICIPATIONS AG (CH) | 2016-08-04 | — | — | US | disclosed |
| EP-3045455-A1 | HETEROCYCLIC AMIDE COMPOUND AND HERBICIDE | Syngenta Participations AG (CH) | 2016-07-20 | — | — | EP | disclosed |
| WO-2014105664-A1 | PIPERAZINE-SUBSTITUTED [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINE COMPOUNDS WITH A2A ANTAGONIST PROPERTIES | MERCK SHARP & DOHME CORP. (US) | 2014-07-03 | — | — | WO | disclosed |
| WO-2014101113-A1 | PIPERAZINE-SUBSTITUTED 7-METHOXY-[1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINE COMPOUNDS WITH A2A ANTAGONIST PROPERTIES | MERCK SHARP & DOHME CORP. (US) | 2014-07-03 | — | — | WO | disclosed |
| US-20140179673-A1 | PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | GILEAD CALISTOGA LLC (US) | 2014-06-26 | — | — | US | disclosed |
| WO-2014100765-A1 | SUBSTITUTED PYRIMIDINE AMINOALKYL-QUINAZOLONES AS PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | GILEAD CALISTOGA LLC (US) | 2014-06-26 | — | — | WO | disclosed |
| US-20140057916-A1 | SUBSTITUTED 4-PYRIDONES AND THEIR USE AS INHIBITORS OF NEUTROPHIL ELASTASE ACTIVITY | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-02-27 | — | — | US | disclosed |
| EP-2370442-B9 | 3-Aminocyclopentanecarboxamides as chemokine receptor modulators | PFIZER (US) | 2013-09-04 | — | — | EP | disclosed |
| US-20130197008-A1 | 3-AMINOCYCLOPENTANECARBOXAMIDES AS CHEMOKINE RECEPTOR AGONISTS | PFIZER INC. (US) | 2013-08-01 | — | — | US | disclosed |
| EP-2370442-B1 | 3-Aminocyclopentanecarboxamides as chemokine receptor modulators | PFIZER (US) | 2013-04-24 | — | — | EP | disclosed |
| US-8268848-B2 | Cyclopropane compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2012-09-18 | — | — | US | disclosed |
| US-20120095031-A1 | CYCLOPROPANE COMPOUND | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2012-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130197008-A1 | 3-AMINOCYCLOPENTANECARBOXAMIDES AS CHEMOKINE RECEPTOR AGONISTS | ACKR3, CCR2, CCR5 | UHRF1 4877/4885HDAC4 2656/4885HDAC1 1405/4885 |
| US-20200390100-A1 | SUBSTITUTED N-HETEROCYCLYL- AND N-HETEROARYL-TETRAHYDROPYRIMIDINONES AND THE SALTS THEREOF, AND THE USE OF SAME AS HERBICIDAL ACTIVE SUBSTANCES | DDT, NOTUM, AGPS | UHRF1 3487/4885HDAC4 1929/4885HDAC1 821/4885 |
| US-20140179673-A1 | PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | PIK3CA, PIK3R5, PIK3R4 | UHRF1 4195/4885HDAC4 1752/4885HDAC1 593/4885 |
| US-20120095031-A1 | CYCLOPROPANE COMPOUND | HCRTR1, HCRTR2, CNR1 | UHRF1 3348/4885HDAC4 1764/4885HDAC1 813/4885 |
| US-20160221998-A1 | HETEROCYCLIC AMIDE COMPOUND AND HERBICIDE | GLRA1, RER1, H1-4 | UHRF1 1654/4885HDAC4 144/4885HDAC1 101/4885 |
| US-20140057916-A1 | SUBSTITUTED 4-PYRIDONES AND THEIR USE AS INHIBITORS OF NEUTROPHIL ELASTASE ACTIVITY | SERPINB1, ELANE, SERPINB6 | UHRF1 4482/4885HDAC4 896/4885HDAC1 571/4885 |
| US-11780861-B2 | Phosphine reagents for azine fluoroalkylation | PTPN3, PHOSPHO1, SKIC3 | UHRF1 4177/4885HDAC4 2506/4885HDAC1 3370/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.