Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 5/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 4/20 | 0.38 |
| ▸ | GSK3B | P49841 | 3/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.38 |
| ▸ | CCND1 | P24385 | 1/20 | 0.38 |
| ▸ | CDK9 | P50750 | 1/20 | 0.38 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26105967 | 0.85 | KDM4E (0.43) | KDM4ESMYD3CDK2CCNE1GSK3B | |
| SCHEMBL7703155 | 0.83 | LMNA (0.47) | FAAHLMNARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL26540428 | 0.81 | CDK2 (0.39) | SMYD3CDK2CCNE1GSK3BCDK1 | |
| SCHEMBL26964748 | 0.81 | RAB9A (0.45) | FAAHLMNARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL973113 | 0.81 | LMNA (0.50) | FAAHLMNARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7699075 | 0.80 | LMNA (0.49) | FAAHLMNARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL5900613 | 0.79 | LMNA (0.48) | FAAHLMNARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL859 | 0.79 | POLB (0.50) | FAAHLMNARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL25348368 | 0.78 | SMN1; SMN2 (0.45) | FAAHLMNARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL24914932 | 0.77 | LMNA (0.43) | FAAHLMNARAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023072096-A1 | TETRAHYDROFURAN-CONTAINING POLYCYCLIC DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF | 优领医药科技(香港)有限公司 | 2023-05-04 | — | — | WO | disclosed |
| CN-116023367-A | Tetrahydrofuran-containing polycyclic derivative, pharmaceutically acceptable salt thereof, and preparation method and application thereof | 优领医药科技(香港)有限公司 | 2023-04-28 | — | — | CN | disclosed |