Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 12/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.37 |
| ▸ | F13A1 | P00488 | 1/20 | 0.37 |
| ▸ | TGM2 | P21980 | 1/20 | 0.37 |
| ▸ | TGM1 | P22735 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26107616 | 1.00 | HSD11B1 (0.41) | HSD11B1TRPV1F13A1TGM2TGM1 | |
| SCHEMBL30591829 | 0.82 | F13A1 (0.43) | HSD11B1TRPV1F13A1TGM2TGM1 | |
| SCHEMBL30591832 | 0.81 | EPHX2 (0.52) | HSD11B1TRPV1CYP3A4 | |
| SCHEMBL26107308 | 0.78 | HTR1A (0.41) | HSD11B1TRPV1F13A1TGM2TGM1 | |
| SCHEMBL30592035 | 0.77 | TRPV1 (0.44) | HSD11B1TRPV1CYP3A4 | |
| SCHEMBL26497743 | 0.74 | GAA (0.41) | HSD11B1TRPV1F13A1TGM2TGM1 | |
| SCHEMBL26107989 | 0.73 | HTR1A (0.40) | HSD11B1TRPV1F13A1TGM2TGM1 | |
| SCHEMBL26106984 | 0.73 | TRPV1 (0.39) | HSD11B1TRPV1 | |
| SCHEMBL26107780 | 0.73 | TRPV1 (0.39) | HSD11B1TRPV1 | |
| SCHEMBL26108503 | 0.72 | PDE10A (0.37) | HSD11B1TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023183768-A2 | SMALL MOLECULE INHIBITORS OF TEA DOMAIN FAMILY MEMBERS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2023-09-28 | — | — | WO | disclosed |