Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | F13A1 | P00488 | 1/20 | 0.37 |
| ▸ | TGM2 | P21980 | 1/20 | 0.37 |
| ▸ | TGM1 | P22735 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26107989 | 0.86 | HTR1A (0.40) | HTR1AHTR1DHTR1BHSD11B1ALDH1A1 | |
| SCHEMBL26106545 | 0.85 | KDM4E (0.45) | HSD11B1ALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL30591753 | 0.82 | HSD11B1 (0.44) | HTR1AHTR1DHTR1BHSD11B1ALDH1A1 | |
| SCHEMBL26105982 | 0.82 | HSD11B1 (0.44) | HTR1AHTR1DHTR1BHSD11B1ALDH1A1 | |
| SCHEMBL26107616 | 0.78 | HSD11B1 (0.41) | HSD11B1TRPV1F13A1TGM2TGM1 | |
| SCHEMBL26106788 | 0.78 | HSD11B1 (0.41) | HSD11B1TRPV1F13A1TGM2TGM1 | |
| SCHEMBL26497738 | 0.74 | GAA (0.42) | HTR1AHTR1DHTR1BHSD11B1ALDH1A1 | |
| SCHEMBL26108503 | 0.73 | PDE10A (0.37) | HSD11B1TRPV1 | |
| SCHEMBL26103628 | 0.72 | CNR2 (0.45) | HSD11B1KDM4EMAPTHTTTRPV1 | |
| SCHEMBL26104302 | 0.71 | SCN10A (0.44) | HSD11B1ALDH1A1KDM4ELMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023183768-A2 | SMALL MOLECULE INHIBITORS OF TEA DOMAIN FAMILY MEMBERS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2023-09-28 | — | — | WO | disclosed |