Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | GAPDH | P04406 | 1/20 | 0.31 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.31 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26219 | 0.85 | ESR1 (0.38) | ESR1ALDH1A1MAPT | |
| SCHEMBL16016767 | 0.79 | ESR1 (0.42) | ESR1ALDH1A1MAPT | |
| SCHEMBL25432 | 0.74 | ESR1 (0.49) | ESR1ALDH1A1MAPT | |
| SCHEMBL26858 | 0.70 | HCAR3 (0.41) | ALDH1A1MAPT | |
| SCHEMBL26859 | 0.68 | MAPT (0.35) | ALDH1A1MAPT | |
| SCHEMBL16016753 | 0.67 | ESR1 (0.55) | ESR1ALDH1A1MAPT | |
| SCHEMBL16016718 | 0.65 | THRA (0.41) | ESR1ALDH1A1MAPT | |
| SCHEMBL26165 | 0.64 | LMNA (0.49) | ALDH1A1MAPT | |
| SCHEMBL16016735 | 0.60 | THRA (0.41) | MAPT | |
| SCHEMBL16016739 | 0.60 | PDK1 (0.44) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012024776-A1 | BLOCK SYNTHESIS OF OLIGORIBONUCLEOTIDES | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2012-03-01 | — | — | WO | disclosed |