Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.43 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25650 | 0.88 | LMNA (0.51) | LMNAPOLBPRMT5WDR77ALDH1A1 | |
| SCHEMBL14731556 | 0.84 | ALDH1A1 (0.44) | LMNAPOLBPRMT5WDR77ALDH1A1 | |
| SCHEMBL26247 | 0.79 | LMNA (0.56) | LMNAPOLBPRMT5WDR77ALDH1A1 | |
| SCHEMBL16016718 | 0.77 | THRA (0.41) | LMNAPOLBALDH1A1NPC1RAB9A | |
| SCHEMBL16016763 | 0.77 | THRA (0.40) | LMNAPOLBALDH1A1NPC1RAB9A | |
| Bromide SCHEMBL20203 | 0.74 | LMNA (0.48) | LMNAPOLBPRMT5WDR77ALDH1A1 | |
| SCHEMBL25432 | 0.74 | ESR1 (0.49) | LMNAPOLBALDH1A1NPC1RAB9A | |
| SCHEMBL16016735 | 0.71 | THRA (0.41) | GAAMAPTHCAR3THRATHRB | |
| Bromide SCHEMBL12474014 | 0.71 | ALDH1A1 (0.47) | LMNAPOLBPRMT5WDR77ALDH1A1 | |
| SCHEMBL16016739 | 0.69 | PDK1 (0.44) | LMNAPOLBALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026142-A1 | IONIC TAGS FOR SYNTHESIS OF OLIGORIBONUCLEOTIDES | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2013-02-28 | — | — | WO | disclosed |
| WO-2012024776-A1 | BLOCK SYNTHESIS OF OLIGORIBONUCLEOTIDES | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2012-03-01 | — | — | WO | disclosed |