SCHEMBL2612596

SCHEMBL2612596

CC(C)(C)CC(C)(C)c1cc(Cc2cc(C(C)(C)CC(C)(C)C)cc(-n3n4c5ccccc5n34)c2O)c(O)c(-n2n3c4ccccc4n23)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP3A4 P08684 5/20 0.40
▸ HIF1A Q16665 2/20 0.40
▸ HSD17B10 Q99714 2/20 0.40
▸ IDH1 O75874 1/20 0.40
▸ ALDH1A1 P00352 1/20 0.40
▸ CYP2C9 P11712 1/20 0.40
▸ ALOX15 P16050 1/20 0.40
▸ USP2 O75604 2/20 0.40
▸ SMN1; SMN2 Q16637 2/20 0.40
▸ MEN1 O00255 1/20 0.40
▸ ESR1 P03372 1/20 0.40
▸ TP53 P04637 1/20 0.40
▸ PGR P06401 1/20 0.40
▸ ADORA3 P0DMS8 1/20 0.40
▸ AR P10275 1/20 0.40
▸ MAPT P10636 1/20 0.40
▸ DRD1 P21728 1/20 0.40
▸ PTGS1 P23219 1/20 0.40
▸ SLC6A2 P23975 1/20 0.40
▸ PDE4A P27815 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13652843 0.92 BCL2 (0.39) CYP3A4HIF1AHSD17B10IDH1ALDH1A1
SCHEMBL2608675 0.92 CYP3A4 (0.40) CYP3A4HIF1AHSD17B10IDH1ALDH1A1
SCHEMBL10031633 0.91 CYP3A4 (0.40) CYP3A4HIF1AHSD17B10IDH1ALDH1A1
SCHEMBL14513849 0.89 CYP3A4 (0.34) CYP3A4HIF1AHSD17B10IDH1ALDH1A1
SCHEMBL19413908 0.84 CYP3A4 (0.33) CYP3A4HIF1AHSD17B10IDH1ALDH1A1
SCHEMBL9002356 0.81 CYP3A4 (0.45) CYP3A4HIF1AHSD17B10IDH1ALDH1A1
SCHEMBL2612597 0.81 SHBG (0.36) CYP3A4HIF1AHSD17B10IDH1ALDH1A1
SCHEMBL12733195 0.80 HSPA5 (0.44) CYP3A4HIF1AHSD17B10ALDH1A1CYP2C9
SCHEMBL17171809 0.80 CYP3A4 (0.36) CYP3A4HIF1AHSD17B10IDH1ALDH1A1
SCHEMBL225142 0.79 KCNMA1 (0.45) CYP3A4HIF1AHSD17B10IDH1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9777138-B2 Latent additive and composition containing latent additive ADEKA CORPORATION (JP) 2017-10-03 — — US disclosed
US-9777138-B2 Latent additive and composition containing latent additive ADEKA CORPORATION (JP) 2017-10-03 — — US disclosed
US-9498653-B2 Sunscreen cosmetic composition containing ultraviolet absorber ADEKA CORPORATION (JP) 2016-11-22 — — US disclosed
US-9274422-B2 Photosensitive resin composition, method for forming pattern-cured film using photosensitive resin composition, and electronic component HITACHI CHEMICAL DUPONT MICROSYSTEMS, LTD. (JP) 2016-03-01 — — US disclosed
US-9274422-B2 Photosensitive resin composition, method for forming pattern-cured film using photosensitive resin composition, and electronic component HITACHI CHEMICAL DUPONT MICROSYSTEMS, LTD. (JP) 2016-03-01 — — US disclosed
US-20150291772-A1 LATENT ADDITIVE AND COMPOSITION CONTAINING LATENT ADDITIVE ADEKA CORPORATION (JP) 2015-10-15 — — US disclosed
US-20150291772-A1 LATENT ADDITIVE AND COMPOSITION CONTAINING LATENT ADDITIVE ADEKA CORPORATION (JP) 2015-10-15 — — US disclosed
US-20140120462-A1 PHOTOSENSITIVE RESIN COMPOSITION, METHOD FOR FORMING PATTERN-CURED FILM USING PHOTOSENSITIVE RESIN COMPOSITION, AND ELECTRONIC COMPONENT HITACHI CHEMICAL DUPONT MICROSYSTEMS, LTD. (JP) 2014-05-01 — — US disclosed
US-20140120462-A1 PHOTOSENSITIVE RESIN COMPOSITION, METHOD FOR FORMING PATTERN-CURED FILM USING PHOTOSENSITIVE RESIN COMPOSITION, AND ELECTRONIC COMPONENT HITACHI CHEMICAL DUPONT MICROSYSTEMS, LTD. (JP) 2014-05-01 — — US disclosed
EP-2474302-A1 SUNSCREEN COSMETIC COMPOSITION CONTAINING ULTRAVIOLET ABSORBER Adeka Corporation (JP) 2012-07-11 — — EP disclosed
US-7968019-B2 Optical compensation film, method for producing optical compensation film, polarization plate and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2011-06-28 — — US disclosed
US-7815823-B2 Optical film, manufacturing method of optical film, optical compensating film, manufacturing method of optical compensating film, polarizing plate, and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2010-10-19 — — US disclosed
US-20100137578-A1 CELLULOSE ESTER FILM FOR OPTICAL USE, AND POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY USING SUCH CELLULOSE ESTER FILM FOR OPTICAL USE KONICA MINOLTA OPTO, INC. (JP) 2010-06-03 — — US disclosed
US-20090246416-A1 OPTICAL FILM, METHOD OF MANUFACTURING THE SAME, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE KONICA MINOLTA OPTO, INC. (JP) 2009-10-01 — — US disclosed
US-20080122128-A1 Method for producing optical film KONICA MINOLTA OPTO, INC. (JP) 2008-05-29 — — US disclosed
US-20080122128-A1 Method for producing optical film KONICA MINOLTA OPTO, INC. (JP) 2008-05-29 — — US disclosed
US-20080029933-A1 Aromatic Polycarbonate Resin Composition, And Substrate For Optical Information-Recording Media, Transparent Optical Article, Lighting Appliance Cover And Transparent Member For Vehicles Comprising It MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2008-02-07 — — US disclosed
US-20070218218-A1 Cellulose acylate optical film, producing method thereof, polarizing plate and liquid crystal display using the same KONICA MINOLTA OPTO, INC. (JP) 2007-09-20 — — US disclosed
US-7189501-B2 Silver halide color photographic photosensitive material FUJI PHOTO FILM CO., LTD. (JP) 2007-03-13 — — US disclosed
US-7189501-B2 Silver halide color photographic photosensitive material FUJI PHOTO FILM CO., LTD. (JP) 2007-03-13 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150291772-A1 LATENT ADDITIVE AND COMPOSITION CONTAINING LATENT ADDITIVE TCF7L2, LUC7L2, TLL2 CYP3A4 503/4885HIF1A 2477/4885HSD17B10 22/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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