Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 12/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 10/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30581690 | 1.00 | TRPV4 (0.38) | TRPV4ESR1ESR2ENPP2CYP11B2 | |
| SCHEMBL25153566 | 0.77 | ALDH1A1 (0.45) | ENPP2AR | |
| SCHEMBL1668130 | 0.76 | ENPP2 (0.37) | TRPV4ESR2ENPP2CYP11B2CYP11B1 | |
| SCHEMBL29950793 | 0.76 | ENPP2 (0.37) | TRPV4ESR2ENPP2CYP11B2CYP11B1 | |
| SCHEMBL29957365 | 0.75 | CES2 (0.37) | ENPP2 | |
| SCHEMBL1364743 | 0.75 | CES2 (0.37) | ENPP2 | |
| SCHEMBL14920227 | 0.74 | TRPV4 (0.43) | TRPV4ESR1ESR2CYP11B2CYP11B1 | |
| SCHEMBL29955536 | 0.73 | AR (0.37) | TRPV4ENPP2AR | |
| SCHEMBL365967 | 0.73 | TRPV4 (0.46) | TRPV4ESR1ESR2CYP11B2CYP11B1 | |
| SCHEMBL6651902 | 0.72 | TRPV4 (0.48) | TRPV4CYP11B2CYP11B1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250206724-A1 | SUBSTITUTED 3-AMINO INDAZOLE DERIVATIVES AS KINASE INHIBITORS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2025-06-26 | — | — | US | disclosed |
| WO-2023186773-A1 | SUBSTITUTED 3-AMINO INDAZOLE DERIVATIVES AS KINASE INHIBITORS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2023-10-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250206724-A1 | SUBSTITUTED 3-AMINO INDAZOLE DERIVATIVES AS KINASE INHIBITORS | CDK1, CDK11A, CDK3 | TRPV4 4562/4885ESR1 2047/4885ESR2 2048/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.