Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | IGF1R | P08069 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | KDM1A | O60341 | 4/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10819320 | 0.77 | L3MBTL1 (0.61) | HTR1AMAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL30013758 | 0.77 | MAPK14 (0.49) | HTR1AGRM2MAPTMAPK1TDP1 | |
| SCHEMBL23723738 | 0.77 | MAPK14 (0.49) | HTR1AGRM2MAPTMAPK1TDP1 | |
| SCHEMBL8320729 | 0.74 | MAPK14 (0.46) | HTR1AMAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL16094113 | 0.74 | MAPK14 (0.49) | HTR1AMAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL18399039 | 0.72 | ALOX5AP (0.41) | HTR1ASLC6A2SLC6A4SLC6A3ALOX5AP | |
| SCHEMBL30666902 | 0.72 | POLB (0.44) | HTR1AMAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL30666961 | 0.72 | MAPT (0.56) | HTR1AMAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL17224562 | 0.72 | MAPT (0.56) | HTR1AMAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL2339072 | 0.72 | LTA4H (0.64) | HTR1AMAPTMAPK1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023193760-A1 | COMPOUNDS AND METHODS OF TREATING CANCERS | CULLGEN (SHANGHAI) , INC. (CN) | 2023-10-12 | — | — | WO | disclosed |