SCHEMBL26147157

SCHEMBL26147157

CCCCc1ccc2c(c1)c1cc3c4cc(CCCC)ccc4n(-c4ccc(-c5ccccc5)cc4)c3cc1n2-c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 2/20 0.44
EP300 Q09472 1/20 0.42
KAT2A Q92830 1/20 0.42
KAT2B Q92831 1/20 0.42
RORA P35398 2/20 0.42
RORC P51449 2/20 0.42
RORB Q92753 2/20 0.42
PLA2G4A P47712 1/20 0.40
PSMB5 P28074 1/20 0.39
PGR P06401 2/20 0.38
RARB P10826 1/20 0.38
MAPK8 P45983 1/20 0.37
UCHL3 P15374 1/20 0.37
DHODH Q02127 1/20 0.36
KDM4E B2RXH2 1/20 0.36
ATM Q13315 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
PTGES O14684 1/20 0.36
CTSV O60911 1/20 0.36
CTSL P07711 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26150756 0.96 KDM4E (0.43) HSD11B1EP300KAT2AKAT2BRORA
SCHEMBL13932483 0.89 UCHL3 (0.43) HSD11B1EP300KAT2AKAT2BRORA
SCHEMBL24914622 0.89 HSD11B1 (0.40) HSD11B1EP300KAT2AKAT2BRORA
SCHEMBL10067556 0.88 RORA (0.47) HSD11B1EP300KAT2AKAT2BRORA
SCHEMBL13932547 0.88 RORA (0.47) HSD11B1EP300KAT2AKAT2BRORA
SCHEMBL13776939 0.88 RORA (0.47) HSD11B1EP300KAT2AKAT2BRORA
SCHEMBL13620181 0.88 HSD11B1 (0.42) HSD11B1EP300KAT2AKAT2BRORA
SCHEMBL10110923 0.86 HSD11B1 (0.56) HSD11B1EP300KAT2AKAT2BRORA
SCHEMBL262517 0.86 RORA (0.42) HSD11B1EP300KAT2AKAT2BRORA
SCHEMBL262206 0.86 EP300 (0.43) HSD11B1EP300KAT2AKAT2BRORA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230157165-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2023-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230157165-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME L1CAM, MCM2, MAL2 HSD11B1 4610/4885EP300 3181/4885KAT2A 2671/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.