Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | FAAH | O00519 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2225221 | 0.98 | PRMT6 (0.62) | SMN1; SMN2ALDH1A1TDP1PRMT6KDM4E | |
| SCHEMBL11192726 | 0.86 | PRMT6 (0.78) | SMN1; SMN2ALDH1A1TDP1PRMT6KDM4E | |
| SCHEMBL11339852 | 0.86 | PRMT6 (0.78) | SMN1; SMN2ALDH1A1TDP1PRMT6KDM4E | |
| SCHEMBL807251 | 0.82 | NCF1 (0.66) | SMN1; SMN2ALDH1A1KDM4EHIF1AHRH3 | |
| SCHEMBL18919824 | 0.82 | MEN1 (0.66) | SMN1; SMN2ALDH1A1KDM4ESIGMAR1FAAH | |
| SCHEMBL29671335 | 0.82 | MEN1 (0.66) | SMN1; SMN2ALDH1A1KDM4ESIGMAR1FAAH | |
| SCHEMBL3720580 | 0.82 | MC4R (0.62) | PRMT6HRH3SIGMAR1FAAH | |
| SCHEMBL2923930 | 0.82 | SIGMAR1 (0.62) | TDP1HRH3SIGMAR1FAAH | |
| SCHEMBL13382006 | 0.82 | ALDH1A1 (0.59) | SMN1; SMN2ALDH1A1TDP1KDM4ESIGMAR1 | |
| SCHEMBL18946202 | 0.80 | LMNA (0.62) | PRMT6SIGMAR1CYP2C19FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120077042-A | 3A,4,5, 6-tetrahydro-1H-pyrazolo [3,4-C ] pyridin-7 (7 AH) -one derivatives as factor XIIa inhibitors | 卡尔维斯塔制药有限公司 | 2025-05-30 | — | — | CN | disclosed |
| WO-2023077216-A1 | HEAT SHOCK PROTEIN 90 (HSP90) INHIBITORS FOR TREATING FUNGAL INFECTIONS AND METHODS OF USE THEREOF | BRIGHT ANGEL THERAPEUTICS INC. (CA) | 2023-05-11 | — | — | WO | disclosed |