Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 10/20 | 0.77 |
| ▸ | GABRA5 | P31644 | 10/20 | 0.77 |
| ▸ | GABRA3 | P34903 | 9/20 | 0.77 |
| ▸ | GABRA2 | P47869 | 9/20 | 0.77 |
| ▸ | GABRG2 | P18507 | 8/20 | 0.77 |
| ▸ | GABRB3 | P28472 | 8/20 | 0.77 |
| ▸ | GABRB2 | P47870 | 7/20 | 0.77 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.77 |
| ▸ | CCKBR | P32239 | 1/20 | 0.77 |
| ▸ | MC3R | P41968 | 1/20 | 0.77 |
| ▸ | GHSR | Q92847 | 1/20 | 0.77 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | CASP4 | P49662 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | CASP9 | P55211 | 1/20 | 0.45 |
| ▸ | CASP6 | P55212 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TSPO | P30536 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Flunitrazepam SCHEMBL8812488 | 0.87 | GABRA1 (1.00) | GABRA1GABRA5GABRA3GABRA2GABRG2 | |
| Flunitrazepam SCHEMBL29372584 | 0.87 | GABRA1 (1.00) | GABRA1GABRA5GABRA3GABRA2GABRG2 | |
| Flunitrazepam SCHEMBL29902314 | 0.87 | GABRA1 (1.00) | GABRA1GABRA5GABRA3GABRA2GABRG2 | |
| Flunitrazepam SCHEMBL44169 | 0.87 | GABRA1 (1.00) | GABRA1GABRA5GABRA3GABRA2GABRG2 | |
| Flunitrazepam SCHEMBL16922172 | 0.87 | GABRA1 (1.00) | GABRA1GABRA5GABRA3GABRA2GABRG2 | |
| Flunitrazepam SCHEMBL6703617 | 0.82 | GABRA1 (0.90) | GABRA1GABRA5GABRA3GABRA2GABRG2 | |
| Flunitrazepam SCHEMBL27607836 | 0.82 | GABRA1 (0.90) | GABRA1GABRA5GABRA3GABRA2GABRG2 | |
| Flunitrazepam SCHEMBL11140334 | 0.80 | GABRA1 (0.85) | GABRA1GABRA5GABRA3GABRA2GABRG2 | |
| Nimetazepam SCHEMBL29374297 | 0.79 | LMNA (1.00) | GABRA1GABRA5GABRA3GABRA2GABRG2 | |
| Nimetazepam SCHEMBL79886 | 0.79 | LMNA (1.00) | GABRA1GABRA5GABRA3GABRA2GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120095217-A1 | FLUORINE CONTAINING COMPOUNDS AND METHODS OF USE THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2012-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120095217-A1 | FLUORINE CONTAINING COMPOUNDS AND METHODS OF USE THEREOF | FLI1, CDC73, FOS | GABRA1 1880/4885GABRA5 2062/4885GABRA3 1497/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.