Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
| ▸ | OGA | O60502 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.30 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26157092 | 0.85 | ALDH1A1 (0.37) | ALDH1A1TSHRL3MBTL1MAPTAOC3 | |
| SCHEMBL26157228 | 0.80 | KDM4E (0.36) | ALDH1A1TSHRL3MBTL1MAPTAOC3 | |
| SCHEMBL18600479 | 0.74 | GPR119 (0.52) | GPR119 | |
| SCHEMBL26511727 | 0.68 | GPR119 (0.49) | AOC3OGAGPR119HPGD | |
| SCHEMBL26157097 | 0.67 | TSHR (0.46) | ALDH1A1TSHRL3MBTL1MAPTPOLB | |
| SCHEMBL12523970 | 0.67 | GPR119 (0.50) | ALDH1A1TSHRL3MBTL1MAPTOGA | |
| SCHEMBL23483105 | 0.67 | ALDH1A1 (0.42) | ALDH1A1TSHRL3MBTL1MAPTPOLB | |
| SCHEMBL18601726 | 0.66 | ATM (0.41) | ACHEGPR119 | |
| SCHEMBL23073770 | 0.66 | TSHR (0.45) | ALDH1A1TSHRL3MBTL1MAPTACHE | |
| SCHEMBL5240697 | 0.66 | SIGMAR1 (0.37) | ALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023093728-A1 | BRM SELECTIVE DEGRADATION AGENT COMPOUND AND USE THEREOF | 江苏先声药业有限公司 | 2023-06-01 | — | — | WO | disclosed |