Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.49 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.49 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25650 | 0.83 | LMNA (0.51) | LMNAPOLBPRMT5WDR77PDK1 | |
| Bromide SCHEMBL22500 | 0.83 | LMNA (0.53) | LMNAPOLBPRMT5WDR77PDK1 | |
| Bromide SCHEMBL12474018 | 0.82 | PDK1 (0.52) | LMNAPOLBPRMT5WDR77PDK1 | |
| SCHEMBL26165 | 0.79 | LMNA (0.49) | LMNAPOLBPRMT5WDR77ALDH1A1 | |
| SCHEMBL26456319 | 0.78 | ALDH1A1 (0.52) | LMNAPOLBPRMT5WDR77PDK1 | |
| SCHEMBL1468345 | 0.77 | LMNA (0.59) | LMNAPOLBPRMT5WDR77ALDH1A1 | |
| SCHEMBL28102683 | 0.77 | MEN1 (0.66) | LMNAPOLBPRMT5WDR77ALDH1A1 | |
| SCHEMBL3406144 | 0.77 | ALDH1A1 (0.70) | LMNAPOLBPRMT5WDR77ALDH1A1 | |
| SCHEMBL14428567 | 0.76 | PDK1 (0.62) | LMNAPDK1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL28079519 | 0.75 | LMNA (0.63) | LMNAPOLBPRMT5WDR77ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210300954-A1 | IONIC TAGS FOR SYNTHESIS OF OLIGORIBONUCLEOTIDES | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIV (CA) | 2021-09-30 | — | — | US | disclosed |
| US-11014948-B2 | Ionic tags for synthesis of oligoribonucleotides | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2021-05-25 | — | — | US | disclosed |
| US-9920084-B2 | Ionic tags for synthesis of oligoribonucleotides | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2018-03-20 | — | — | US | disclosed |
| US-20140256926-A1 | Ionic Tags for Synthesis of Oligoribonucleotides | HONG KONG POLYTECHNIC UNIVERSITY (HK) | 2014-09-11 | — | — | US | disclosed |
| WO-2013026142-A1 | IONIC TAGS FOR SYNTHESIS OF OLIGORIBONUCLEOTIDES | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2013-02-28 | — | — | WO | disclosed |
| WO-2012024776-A1 | BLOCK SYNTHESIS OF OLIGORIBONUCLEOTIDES | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2012-03-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11014948-B2 | Ionic tags for synthesis of oligoribonucleotides | RNGTT, OSTC, DTYMK | LMNA 2711/4885POLB 100/4885PRMT5 3761/4885 |
| US-20210300954-A1 | IONIC TAGS FOR SYNTHESIS OF OLIGORIBONUCLEOTIDES | RNGTT, OSTC, DTYMK | LMNA 2711/4885POLB 100/4885PRMT5 3761/4885 |
| US-20140256926-A1 | Ionic Tags for Synthesis of Oligoribonucleotides | RNGTT, OSTC, OSGEP | LMNA 2643/4885POLB 108/4885PRMT5 3852/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.