SCHEMBL2961857

SCHEMBL2961857

C=C(C)C(=O)OO[SiH2]OC(=O)C(=C)C

nearest known ligand 0.42

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.42
TSHR P16473 3/20 0.34
THRB P10828 1/20 0.32
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL261665 0.83 ALDH1A1 (0.52) ALDH1A1TSHRTHRBTDP1
SCHEMBL10340727 0.76
SCHEMBL27718680 0.76 ALDH1A1 (0.46) ALDH1A1TSHRTHRBTDP1
SCHEMBL30647511 0.76
SCHEMBL829058 0.74
SCHEMBL29042198 0.74
SCHEMBL2215339 0.74 ALDH1A1 (0.61) ALDH1A1TSHRTHRBTDP1
SCHEMBL29151765 0.71 THRB (0.44) ALDH1A1TSHRTHRB
SCHEMBL4979158 0.71 ALDH1A1 (0.41) ALDH1A1TSHRTHRB
SCHEMBL28565199 0.71 ALDH1A1 (0.41) ALDH1A1TSHRTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12577345-B2 Radiation blockers for contact lenses COOPERVISION INTERNATIONAL LIMITED (GB) 2026-03-17 US disclosed
EP-4519721-B1 RADIATION BLOCKERS FOR CONTACT LENSES COOPERVISION INT LTD (GB) 2025-10-01 EP disclosed
EP-4519721-A1 RADIATION BLOCKERS FOR CONTACT LENSES CooperVision International Limited (GB) 2025-03-12 EP disclosed
WO-2024236287-A1 RADIATION BLOCKERS FOR CONTACT LENSES COOPERVISION INTERNATIONAL LIMITED (GB) 2024-11-21 WO disclosed
EP-4465098-A2 RADIATION BLOCKERS FOR CONTACT LENSES CooperVision International Limited (GB) 2024-11-20 EP disclosed
EP-4465097-A1 RADIATION BLOCKERS FOR CONTACT LENSES CooperVision International Limited (GB) 2024-11-20 EP disclosed
CN-113248652-B Photocurable composition for sealing organic light-emitting device 浙江华显光电科技有限公司 2022-09-16 CN disclosed
US-7772351-B2 grafted onto an ethylenically unsaturated monomer; paper, textile, detergents, paints; COATEX S.A.S. (FR) 2010-08-10 US disclosed
US-20060106186-A1 grafted onto an ethylenically unsaturated monomer; paper, textile, detergents, paints; COATEX S.A.S. (FR) 2006-05-18 US disclosed
US-6893595-B1 Method for providing coated moulded polymeric articles BIOCOMPATIBLES UK LIMITED (GB) 2005-05-17 US disclosed
EP-1109853-B1 METHOD FOR PROVIDING COATED MOULDED POLYMERIC ARTICLES BIOCOMPATIBLES UK LTD (GB) 2004-09-22 EP disclosed
EP-1109853-A1 METHOD FOR PROVIDING COATED MOULDED POLYMERIC ARTICLES BIOCOMPATIBLES LTD. (GB) 2001-06-27 EP disclosed
WO-2000004078-A1 METHOD FOR PROVIDING COATED MOULDED POLYMERIC ARTICLES BIOCOMPATIBLES LIMITED (GB) 2000-01-27 WO disclosed
US-5256723-A Cartridge having hardenable cycloaliphatic derivatives for bore hole-filling masses HILTI AKTIENGESELLSCHAFT (LI) 1993-10-26 US disclosed
US-5157072-A For curing unsaturated polyesters and vinyl esters; fillers, phenol-formaldehyde resins, additives HILTI AKTIENGESELLSCHAFT (LI) 1992-10-20 US disclosed
EP-0362137-A2 Molded polymers with hydrophilic surfaces, and process for making them CIBA-GEIGY AG (CH) 1990-04-04 EP disclosed
EP-0075004-A1 SILICONE METHACRYLATE HYDROGELS FOR CONTACT LENSES McCARRY, John D. (US) 1983-03-30 EP disclosed
WO-1982003397-A1 SILICONE METHACRYLATE HYDROGELS FOR CONTACT LENSES MCCARRY JOHN D (US) 1982-10-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12577345-B2 Radiation blockers for contact lenses TBL3, TTLL12, TBL2 ALDH1A1 3091/4885TSHR 353/4885THRB 273/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.