Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL261665 | 0.81 | ALDH1A1 (0.52) | ALDH1A1TSHRTHRB | |
| SCHEMBL10340727 | 0.75 | — | — | |
| SCHEMBL27718680 | 0.75 | ALDH1A1 (0.46) | ALDH1A1TSHRTHRB | |
| SCHEMBL829058 | 0.73 | — | — | |
| SCHEMBL7178369 | 0.72 | — | — | |
| SCHEMBL2961857 | 0.71 | ALDH1A1 (0.42) | ALDH1A1TSHRTHRB | |
| SCHEMBL29151765 | 0.70 | THRB (0.44) | ALDH1A1TSHRTHRB | |
| SCHEMBL28565199 | 0.70 | ALDH1A1 (0.41) | ALDH1A1TSHRTHRB | |
| SCHEMBL28411732 | 0.69 | — | — | |
| SCHEMBL6137384 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1927882-B1 | Contact lens | NOVARTIS AG (CH) | 2015-09-23 | — | — | EP | disclosed |
| EP-1236068-B1 | CONTACT LENS | NOVARTIS AG (CH) | 2008-08-27 | — | — | EP | disclosed |
| EP-1927882-A2 | Contact lens | Novartis AG (CH) | 2008-06-04 | — | — | EP | disclosed |
| US-7201481-B2 | Interpolymerization product of a (a) hydrophilic monomer with (b) a tris(siloxy)silyl group- containing monomer, (c) a wide variety of hydrophobic monomers (both aliphatic and aromatic) and usually a (d) polyfluorinated monomer | NOVARTIS AG (CH) | 2007-04-10 | — | — | US | disclosed |
| US-20060012751-A1 | Contact lens | ALCON INC. (CH) | 2006-01-19 | — | — | US | disclosed |
| US-6649722-B2 | Interpolymerization product of a (a) hydrophilic monomer with (b) a tris(siloxy)silyl group- containing monomer, (c) a wide variety of hydrophobic monomers (both aliphatic and aromatic) and usually a (d) polyfluorinated monomer | NOVARTIS AG (CH) | 2003-11-18 | — | — | US | disclosed |
| US-20020107337-A1 | Contact lens | ALCON INC. (CH) | 2002-08-08 | — | — | US | disclosed |