Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | REN | P00797 | 2/20 | 0.41 |
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSH | P09668 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26168283 | 0.88 | CNR1 (0.43) | LTA4HRENCTSKALDH1A1CPB2 | |
| SCHEMBL27272775 | 0.79 | LTA4H (0.39) | LTA4HRENCTSKCPB2CTSL | |
| SCHEMBL11964530 | 0.79 | EPHX1 (0.53) | LTA4HRENCTSKALDH1A1CPB2 | |
| SCHEMBL13879136 | 0.79 | CTSK (0.42) | LTA4HRENCTSKCTSLCTSB | |
| SCHEMBL13954308 | 0.79 | CTSK (0.42) | LTA4HRENCTSKCTSLCTSB | |
| SCHEMBL13235676 | 0.79 | CTSK (0.42) | LTA4HRENCTSKCTSLCTSB | |
| SCHEMBL13971373 | 0.79 | CTSK (0.42) | LTA4HRENCTSKCTSLCTSB | |
| SCHEMBL14321938 | 0.78 | LTA4H (0.43) | LTA4HRENCTSKCTSLCTSB | |
| SCHEMBL26879069 | 0.77 | CPB2 (0.47) | RENCPB2PSMB5 | |
| SCHEMBL13155423 | 0.77 | LTA4H (0.47) | LTA4HCTSKALDH1A1KMT2ACTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024059472-A1 | MACROCYCLIC IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-03-21 | — | — | WO | disclosed |
| WO-2023225661-A1 | MACROCYCLIC IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-11-23 | — | — | WO | disclosed |
| WO-2023102507-A1 | MACROCYCLIC IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-06-08 | — | — | WO | disclosed |