Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.53 |
| ▸ | CTSK | P43235 | 3/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | REN | P00797 | 2/20 | 0.42 |
| ▸ | CTSD | P07339 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10078888 | 0.84 | EPHX1 (0.50) | EPHX1CTSKLTA4HRENCTSD | |
| SCHEMBL13889049 | 0.79 | REN (0.50) | EPHX1CTSKLTA4HRENCTSD | |
| SCHEMBL14321938 | 0.79 | LTA4H (0.43) | CTSKLTA4HRENCTSDCTSL | |
| SCHEMBL26169592 | 0.79 | LTA4H (0.45) | CTSKLTA4HRENALDH1A1KMT2A | |
| SCHEMBL26168283 | 0.76 | CNR1 (0.43) | CTSKLTA4HRENCTSDALDH1A1 | |
| SCHEMBL16054267 | 0.75 | ALDH1A1 (0.47) | CTSKLTA4HRENCTSDALDH1A1 | |
| SCHEMBL27272775 | 0.74 | LTA4H (0.39) | CTSKLTA4HRENCPB2CTSL | |
| SCHEMBL8224748 | 0.73 | MMP1 (0.50) | EPHX1ALDH1A1KMT2AMEN1GAA | |
| SCHEMBL9966033 | 0.73 | MMP1 (0.50) | EPHX1ALDH1A1KMT2AMEN1GAA | |
| SCHEMBL416758 | 0.73 | CTSK (0.40) | CTSKLTA4HALDH1A1CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8648094-B2 | IAP BIR domain binding compounds | PHARMASCIENCE, INC. (CA) | 2014-02-11 | — | — | US | disclosed |
| US-20120195915-A1 | IAP BIR domain binding compounds | PHARMASCIENCE INC. (CA) | 2012-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120195915-A1 | IAP BIR domain binding compounds | BIRC5, BIRC2, BIRC3 | EPHX1 4075/4885CTSK 2955/4885LTA4H 3525/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.