SCHEMBL2617344

SCHEMBL2617344

O=C(CCCOCc1ccccc1)N1C(=O)OC[C@@H]1Cc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 8/20 0.50
FAAH O00519 3/20 0.40
ALDH1A1 P00352 1/20 0.40
EPHX2 P34913 1/20 0.39
PPARA Q07869 2/20 0.39
TEAD3 Q99594 1/20 0.38
IDH1 O75874 1/20 0.38
PLA2G1B P04054 1/20 0.37
PLA2G2A P14555 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14243737 1.00 NAAA (0.50) NAAAFAAHALDH1A1EPHX2PPARA
SCHEMBL17756150 1.00 NAAA (0.50) NAAAFAAHALDH1A1EPHX2PPARA
SCHEMBL6599302 0.97 NAAA (0.52) NAAAFAAHALDH1A1EPHX2PPARA
SCHEMBL14243651 0.97 NAAA (0.52) NAAAFAAHALDH1A1EPHX2PPARA
SCHEMBL14243652 0.97 NAAA (0.52) NAAAFAAHALDH1A1EPHX2PPARA
SCHEMBL8828113 0.96 NAAA (0.54) NAAAFAAHALDH1A1EPHX2PPARA
SCHEMBL4299854 0.93 NAAA (0.46) NAAAFAAHALDH1A1PPARAIDH1
SCHEMBL4299858 0.93 NAAA (0.46) NAAAFAAHALDH1A1PPARAIDH1
SCHEMBL19713409 0.93 NAAA (0.46) NAAAFAAHALDH1A1PPARAIDH1
SCHEMBL17762203 0.89 NAAA (0.51) NAAAFAAHALDH1A1PPARAIDH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111440046-B Synthetic method of sex pheromone (S) -14-methyl-1-octadecene of lepidoptera pest phyllocladia persica 塔里木大学 2022-09-16 CN claimed
CN-111440046-A Synthesis method of sex pheromone (S) -14-methyl-1-octadecene of lepidoptera pest peach leaf miner 塔里木大学 2020-07-24 CN claimed
CN-111440046-B Synthetic method of sex pheromone (S) -14-methyl-1-octadecene of lepidoptera pest phyllocladia persica 塔里木大学 2022-09-16 CN disclosed
US-11299480-B2 2-arylsulfonamido-N-arylacetamide derivatized STAT3 inhibitors UNIVERSITY OF HAWAII (US) 2022-04-12 US disclosed
EP-3437640-B1 AGENT FOR TREATING SYNUCLEINOPATHY UNIV TOHOKU (JP) 2021-11-24 EP disclosed
WO-2020251953-A1 STREPTOGRAMIN COMPOSITIONS AND THE USE THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2020-12-17 WO disclosed
CN-111440046-A Synthesis method of sex pheromone (S) -14-methyl-1-octadecene of lepidoptera pest peach leaf miner 塔里木大学 2020-07-24 CN disclosed
US-10709688-B2 Agent for treating synucleinopathy TOHOKU UNIVERSITY (JP) 2020-07-14 US disclosed
US-10709688-B2 Agent for treating synucleinopathy TOHOKU UNIVERSITY (JP) 2020-07-14 US disclosed
CN-111356456-A 2-arylsulfonamido-iV-arylacetamide derived Stat3 inhibitor 夏威夷大学 2020-06-30 CN disclosed
US-20190125726-A1 AGENT FOR TREATING SYNUCLEINOPATHY TOHOKU UNIVERSITY (JP) 2019-05-02 US disclosed
US-20070219192-A1 Certain chemical entities, compositions, and methods CYTOKINETICS, INCORPORATED 2007-09-20 US disclosed
US-20070219192-A1 Certain chemical entities, compositions, and methods CYTOKINETICS, INCORPORATED 2007-09-20 US disclosed
US-20070219192-A1 Certain chemical entities, compositions, and methods CYTOKINETICS, INCORPORATED 2007-09-20 US disclosed
US-20070197481-A1 Certain chemical entities, compositions, and methods CYTOKINETICS, INCORPORATED 2007-08-23 US disclosed
US-20070197481-A1 Certain chemical entities, compositions, and methods CYTOKINETICS, INCORPORATED 2007-08-23 US disclosed
US-20070149516-A1 Certain chemical entities, compositions, and methods CYTOKINETICS, INCORPORATED 2007-06-28 US disclosed
US-20070149516-A1 Certain chemical entities, compositions, and methods CYTOKINETICS, INCORPORATED 2007-06-28 US disclosed
WO-2007056143-A2 CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS CYTOKINETICS, INC. (US) 2007-05-18 WO disclosed
WO-2007056143-A2 CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS CYTOKINETICS, INC. (US) 2007-05-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11299480-B2 2-arylsulfonamido-N-arylacetamide derivatized STAT3 inhibitors STAT3, JAK2, STAT5A NAAA 2957/4885FAAH 4793/4885ALDH1A1 1312/4885
US-20070219192-A1 Certain chemical entities, compositions, and methods KIF5B, KIF2C, PLK1 NAAA 3559/4885FAAH 4312/4885ALDH1A1 2159/4885
US-10709688-B2 Agent for treating synucleinopathy SNCA, PARK7, SYNJ1 NAAA 2707/4885FAAH 1647/4885ALDH1A1 2189/4885
US-20190125726-A1 AGENT FOR TREATING SYNUCLEINOPATHY SNCA, PARK7, SYNJ1 NAAA 2707/4885FAAH 1647/4885ALDH1A1 2189/4885
US-20070197481-A1 Certain chemical entities, compositions, and methods KIF5B, KIF2C, PLK1 NAAA 3559/4885FAAH 4312/4885ALDH1A1 2159/4885
US-20070149516-A1 Certain chemical entities, compositions, and methods KIF5B, KIF2C, PLK1 NAAA 3559/4885FAAH 4312/4885ALDH1A1 2159/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.