SCHEMBL261939

SCHEMBL261939

FC(F)(F)c1ccc2c(c1)c1cc(-c3ccc4c(c3)c3cc(-c5ccc6c(c5)c5cc(C(F)(F)F)ccc5n6-c5ccccc5C(F)(F)F)ccc3n4-c3ccc(-c4c5ccccc5c(-c5ccccc5)c5ccccc45)cc3)ccc1n2-c1ccccc1C(F)(F)F

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.37
PPARG P37231 3/20 0.36
PPARA Q07869 2/20 0.36
ALDH1A1 P00352 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
KIF11 P52732 2/20 0.34
MGAM O43451 1/20 0.34
GAA P10253 1/20 0.34
SI P14410 1/20 0.34
MGAM2 Q2M2H8 1/20 0.34
KDM4E B2RXH2 1/20 0.33
MAPT P10636 1/20 0.33
RORC P51449 1/20 0.33
TACR1 P25103 1/20 0.33
NR3C1 P04150 1/20 0.33
PGR P06401 1/20 0.33
TEAD1 P28347 1/20 0.32
TEAD4 Q15561 1/20 0.32
TEAD2 Q15562 1/20 0.32
TEAD3 Q99594 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL262714 0.98 PPARG (0.37) ESR1PPARGPPARAALDH1A1L3MBTL1
SCHEMBL261871 0.92 L3MBTL1 (0.40) ESR1PPARGPPARAALDH1A1L3MBTL1
SCHEMBL262775 0.92 L3MBTL1 (0.40) ESR1PPARGPPARAALDH1A1L3MBTL1
SCHEMBL10108544 0.91 ALDH1A1 (0.34) ESR1PPARGPPARAALDH1A1L3MBTL1
SCHEMBL262806 0.90 KIF11 (0.44) ESR1PPARGPPARAL3MBTL1KIF11
SCHEMBL262506 0.90 KIF11 (0.44) ESR1PPARGPPARAL3MBTL1KIF11
SCHEMBL262383 0.87 PPARG (0.43) ESR1PPARGPPARAL3MBTL1KIF11
SCHEMBL262726 0.87 KIF11 (0.42) ESR1PPARGPPARAL3MBTL1KIF11
SCHEMBL262729 0.87 KDM4E (0.45) ESR1PPARGPPARAALDH1A1L3MBTL1
SCHEMBL262748 0.87 KIF11 (0.42) ESR1PPARGPPARAL3MBTL1KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9136479-B2 Organic compound, anthracene derivative, and light-emitting element, light-emitting device, and electronic device using the anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-09-15 US disclosed
US-8816098-B2 Organic compound, anthracene derivative, and light-emitting element, light-emitting device, and electronic device using the anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-08-26 US disclosed
US-8530672-B2 Organic compound, anthracene derivative, and light-emitting element, light-emitting device, and electronic device using anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-09-10 US disclosed
US-20120309984-A1 ORGANIC COMPOUND, ANTHRACENE DERIVATIVE, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC DEVICE USING ANTHRACENE DERIVATIVE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-12-06 US disclosed
US-8278655-B2 Organic compound, anthracene derivative, and light-emitting element, light-emitting device, and electronic device using anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-10-02 US disclosed
EP-1972619-B1 Organic compound, anthracene derivative, and light-emitting element, light-emitting device, and electronic device using anthracene derivative SEMICONDUCTOR ENERGY LAB (JP) 2012-08-15 EP disclosed
US-20120104379-A1 ORGANIC COMPOUND, ANTHRACENE DERIVATIVE, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC DEVICE USING ANTHRACENE DERIVATIVE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-05-03 US disclosed
US-8134147-B2 Organic compound, anthracene derivative, and light-emitting element, light-emitting device, and electronic device using anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-03-13 US disclosed
US-8134147-B2 Organic compound, anthracene derivative, and light-emitting element, light-emitting device, and electronic device using anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-03-13 US disclosed
US-20100200847-A1 ORGANIC COMPOUND, ANTHRACENE DERIVATIVE, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC DEVICE USING ANTHRACENE DERIVATIVE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-08-12 US disclosed
US-20100200847-A1 ORGANIC COMPOUND, ANTHRACENE DERIVATIVE, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC DEVICE USING ANTHRACENE DERIVATIVE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-08-12 US disclosed
US-7723722-B2 Organic compound, anthracene derivative, and light-emitting element, light-emitting device, and electronic device using anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-05-25 US disclosed
US-7723722-B2 Organic compound, anthracene derivative, and light-emitting element, light-emitting device, and electronic device using anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-05-25 US disclosed
US-20080242871-A1 N-(9-Aryl-10-anthracenylarylene)carbazole derivatives that are substituted with aditional aromatic amine groups including additional carbzaole rings; light-emitting element that emits blue light at high luminous efficiency and is capable of operation for a long time. SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-10-02 US disclosed
US-20080242871-A1 N-(9-Aryl-10-anthracenylarylene)carbazole derivatives that are substituted with aditional aromatic amine groups including additional carbzaole rings; light-emitting element that emits blue light at high luminous efficiency and is capable of operation for a long time. SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-10-02 US disclosed
EP-1972619-A1 Organic compound, anthracene derivative, and light-emitting element, light-emitting device, and electronic device using anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-09-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120104379-A1 ORGANIC COMPOUND, ANTHRACENE DERIVATIVE, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC DEVICE USING ANTHRACENE DERIVATIVE CYP1A1, XPO7, AMY1A ESR1 147/4885PPARG 1293/4885PPARA 2260/4885
US-20120309984-A1 ORGANIC COMPOUND, ANTHRACENE DERIVATIVE, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC DEVICE USING ANTHRACENE DERIVATIVE CYP1A1, XPO7, AMY1A ESR1 147/4885PPARG 1293/4885PPARA 2260/4885
US-20080242871-A1 N-(9-Aryl-10-anthracenylarylene)carbazole derivatives that are substituted with aditional aromatic amine groups including additional carbzaole rings; light-emitting element that emits blue light at high luminous efficiency and is capable of operation for a long time. CYP1A1, AADAT, AADAC ESR1 1070/4885PPARG 1015/4885PPARA 1508/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.