SCHEMBL261971

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2884596	0.89	ALDH1A1 (0.62)	ALDH1A1KDM4EGAAMEN1MAPT
	SCHEMBL261392	0.81	NPC1 (0.47)	ALDH1A1KDM4EGAAMEN1MAPT
	SCHEMBL20119875	0.79	KDM4E (0.58)	ALDH1A1KDM4EGAAMEN1MAPT
	SCHEMBL13378912	0.78	NPC1 (0.39)	ALDH1A1KDM4EMEN1MAPTKMT2A
	SCHEMBL28960198	0.75	PKM (0.56)	ALDH1A1KDM4EGAAMEN1MAPT
	SCHEMBL12627953	0.73	NPC1 (0.53)	ALDH1A1KDM4EGAAMEN1MAPT
	SCHEMBL20120119	0.73	SMN1; SMN2 (0.59)	ALDH1A1KDM4EGAAMEN1MAPT
	SCHEMBL74692	0.73	CYP1A2 (0.62)	ALDH1A1MEN1KMT2APOLBL3MBTL1
	SCHEMBL28796113	0.72	GAA (0.56)	ALDH1A1KDM4EGAAMEN1MAPT
	SCHEMBL29940979	0.72	GAA (0.56)	ALDH1A1KDM4EGAAMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.