SCHEMBL261979

SCHEMBL261979

C=CC(=O)NCc1ccc(Nc2ccccc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 2/20 0.61
BTK Q06187 2/20 0.51
EGFR P00533 1/20 0.51
ALDH1A1 P00352 2/20 0.50
LMNA P02545 1/20 0.50
CYP2D6 P10635 1/20 0.50
CYP2C19 P33261 1/20 0.50
MMP1 P03956 2/20 0.47
MMP2 P08253 2/20 0.47
MMP9 P14780 2/20 0.47
MT-CO2 P00403 1/20 0.47
CYP2C9 P11712 1/20 0.46
PIM1 P11309 1/20 0.46
NPC1 O15118 2/20 0.45
RAB9A P51151 2/20 0.45
POLB P06746 1/20 0.45
MAOB P27338 1/20 0.45
MEN1 O00255 1/20 0.45
TP53 P04637 1/20 0.45
HPGD P15428 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2720077 0.86 BTK (0.66) TGM2BTKEGFRALDH1A1LMNA
SCHEMBL40744 0.86 TGM2 (0.68) TGM2ALDH1A1LMNACYP2D6CYP2C19
SCHEMBL8995939 0.86 TGM2 (0.59) TGM2BTKEGFRALDH1A1LMNA
Ethylene SCHEMBL6400166 0.84 TGM2 (0.66) TGM2ALDH1A1LMNACYP2D6CYP2C19
SCHEMBL732934 0.84 TGM2 (0.81) TGM2ALDH1A1LMNACYP2D6CYP2C19
SCHEMBL11775423 0.84 TGM2 (0.71) TGM2BTKEGFRALDH1A1LMNA
SCHEMBL19889047 0.83 TGM2 (0.65) TGM2ALDH1A1LMNACYP2D6CYP2C19
SCHEMBL8995937 0.82 TGM2 (0.59) TGM2BTKALDH1A1NPC1RAB9A
Dimethylamine SCHEMBL1263583 0.81 TGM2 (0.62) TGM2BTKEGFRALDH1A1LMNA
SCHEMBL5362600 0.81 MMP1 (0.64) TGM2ALDH1A1LMNACYP2D6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 672 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025102500-A1 NITRILE RUBBER, AND PREPARATION METHOD THEREFOR AND USE THEREOF 中国石油天然气股份有限公司 2025-05-22 WO claimed
US-10858455-B2 Process for the production of water and solvent-free nitrile rubbers ARLANXEO DEUTSCHLAND GMBH (DE) 2020-12-08 US claimed
US-20160369014-A1 PROCESS FOR THE PRODUCTION OF WATER AND SOLVENT-FREE NITRILE RUBBERS ARLANXEO DEUTSCHLAND GMBH (DE) 2016-12-22 US claimed
EP-2478021-B1 Nitrile rubbers and production of same in organic solvents LANXESS DEUTSCHLAND GMBH (DE) 2015-11-04 EP claimed
US-9023914-B2 Nitrile rubbers and production thereof in organic solvents LANXESS DEUTSCHLAND GMBH (DE) 2015-05-05 US claimed
EP-2641909-A1 Transition metal P-N complexes as polymerization catalysts LANXESS Deutschland GmbH (DE) 2013-09-25 EP claimed
US-20120283351-A1 NITRILE RUBBERS AND PRODUCTION THEREOF IN ORGANIC SOLVENTS LANXESS DEUTSCHLAND GMBH (DE) 2012-11-08 US claimed
US-20090131563-A1 Starch-(Meth)Acrylate Graft Copolymer, Oil-Swellable Material and Oil- and Water-Swellable Material Comprising the Same, and Sealing Articles and Packers Prepared from said Swellable Material Yi, Huian (CN) 2009-05-21 US claimed
EP-0508012-B1 A dispersant/antioxidant viscosity index improving lubricant additive ETHYL ADDITIVES CORP (US) 1998-08-05 EP claimed
US-5440000-A Methacrylate and methacrylamide copolymers; for internal combustion engines TEXACO INC. (US) 1995-08-08 US claimed
EP-0331608-B1 Organothioethyl alcohol segmers as antidegradant synergists GOODYEAR TIRE & RUBBER (US) 1995-01-18 EP claimed
EP-0397949-B1 Water based precure paint for rubber articles GOODYEAR TIRE & RUBBER (US) 1994-07-13 EP claimed
EP-0155897-B1 INCORPORATION OF FUNCTIONALIZED MONOMERS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1991-09-04 EP claimed
EP-0251977-B1 AN IMPROVED PROCESS FOR THE INCORPORATION OF FUNCTIONALIZED MONOMERS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1990-06-27 EP claimed
EP-0331608-A1 Organothioethyl alcohol segmers as antidegradant synergists THE GOODYEAR TIRE & RUBBER COMPANY (US) 1989-09-06 EP claimed
US-4806447-A Method of chemically bonding antioxidants into polymeric materials THE GOODYEAR TIRE & RUBBER COMPANY (US) 1989-02-21 US claimed
US-4739014-A USING FREE RADICAL CATALYST THE GOODYEAR TIRE & RUBBER COMPANY (US) 1988-04-19 US claimed
US-4701507-A USING METHYL ISOBUTYL KETONE SOLVENT AND A SOAP THE GOODYEAR TIRE & RUBBER COMPANY (US) 1987-10-20 US claimed
US-4376846-A OIL AND OZONE RESISTANT AND HEAT AGING RESISTANT JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1983-03-15 US claimed
US-4300615-A Fabric composite and rubber reinforced therewith THE GOODYEAR TIRE & RUBBER COMPANY (US) 1981-11-17 US claimed