Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | BTK | Q06187 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4743993 | 0.93 | TGM2 (0.63) | TGM2MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8995961 | 0.86 | MEN1 (0.60) | TGM2MEN1KMT2ASMN1; SMN2BTK | |
| SCHEMBL8995939 | 0.84 | TGM2 (0.59) | TGM2MEN1KMT2ASMN1; SMN2BTK | |
| SCHEMBL261979 | 0.82 | TGM2 (0.61) | TGM2MEN1KMT2ASMN1; SMN2BTK | |
| SCHEMBL8467427 | 0.80 | TGM2 (0.90) | TGM2SMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL732934 | 0.79 | TGM2 (0.81) | TGM2MEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL15338482 | 0.79 | ALDH1A1 (0.59) | MEN1KMT2ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL8476285 | 0.78 | MEN1 (0.60) | TGM2MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8478088 | 0.78 | ALDH1A1 (0.69) | TGM2KMT2ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL23542540 | 0.77 | ALDH1A1 (0.57) | MEN1KMT2ASMN1; SMN2ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0570825-B1 | Tire sidewall composition containing silica having low PH | GOODYEAR TIRE & RUBBER (US) | 1996-08-07 | — | — | EP | disclosed |
| EP-0475215-B1 | Carboxylic acid esters with thio groups | GOODYEAR TIRE & RUBBER (US) | 1994-10-19 | — | — | EP | disclosed |
| EP-0570825-A1 | Tire sidewall composition containing silica having low PH | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1993-11-24 | — | — | EP | disclosed |
| US-5244028-A | Natural rubber or polybutadiene, silica, antidegradation agent, carbon black | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1993-09-14 | — | — | US | disclosed |
| US-5216049-A | A phenolic or amine stabilizer and an organothioalkylene styrene bound to a polymer; aging resistance; rubbers | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1993-06-01 | — | — | US | disclosed |
| EP-0475215-A1 | Carboxylic acid esters with thio groups | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1992-03-18 | — | — | EP | disclosed |
| US-5069819-A | SYNERGISTS FOR CONVENTIONAL PHENOLIC AND AMINE ANTIOXIDANTS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1991-12-03 | — | — | US | disclosed |