SCHEMBL26201551

SCHEMBL26201551

CO[C@@H]1[C@H](OP(=O)(O)OC[C@H]2O[C@@H](n3cnc4c(=O)[nH]c(N)nc43)[C@H](O)[C@@H]2O)[C@@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)OC[C@H]2OC(n3c[n+](C)c4c(=O)[nH]c(N)nc43)[C@H](O)[C@@H]2COCCN(C)C)O[C@H]1n1cnc2c(=O)[nH]c(N)nc21

nearest known ligand 0.53

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
FUT5 Q11128 1/20 0.53
TGM2 P21980 1/20 0.53
KRAS P01116 5/20 0.52
DCPS Q96C86 1/20 0.49
NT5E P21589 1/20 0.49
RNASEL Q05823 5/20 0.48
P2RY2 P41231 1/20 0.47
P2RY4 P51582 1/20 0.47
P2RY6 Q15077 1/20 0.47
P2RX3 P56373 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26622070 0.94 FUT5 (0.55) FUT5TGM2KRASDCPSNT5E
SCHEMBL26622052 0.92 FUT5 (0.55) FUT5TGM2KRASDCPSNT5E
SCHEMBL26201452 0.92 KRAS (0.50) FUT5TGM2KRASDCPSNT5E
SCHEMBL26212713 0.92 KRAS (0.50) FUT5TGM2KRASDCPSNT5E
SCHEMBL26621974 0.92 KRAS (0.50) FUT5TGM2KRASDCPSNT5E
SCHEMBL25584006 0.91 TGM2 (0.62) FUT5TGM2KRASDCPSNT5E
SCHEMBL26622391 0.91 RNASEL (0.55) FUT5TGM2KRASRNASELP2RY2
SCHEMBL26622416 0.90 RNASEL (0.54) FUT5TGM2KRASRNASELP2RY2
SCHEMBL23997752 0.90 TGM2 (0.60) FUT5TGM2KRASDCPSNT5E
SCHEMBL25584010 0.90 TGM2 (0.60) FUT5TGM2KRASDCPSNT5E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230340009-A1 COMPOUNDS FOR RNA CAPPING AND USES THEREOF GUANGZHOU HENOVCOM BIOSCIENCE CO., LTD. (CN) 2023-10-26 US disclosed
WO-2023159930-A1 COMPOUND FOR RNA CAPPING AND APPLICATION OF COMPOUND 广州市恒诺康医药科技有限公司 2023-08-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230340009-A1 COMPOUNDS FOR RNA CAPPING AND USES THEREOF RNGTT, RNMT, NSUN2 FUT5 1516/4885TGM2 2548/4885KRAS 2017/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.