SCHEMBL26201871

SCHEMBL26201871

CCCOC[C@H]1[C@@H](O)[C@H](n2c[n+](C)c3c(=O)[nH]c(N)nc32)O[C@@H]1COP(=O)(O)OP(=O)(O)OP(=O)(O)OC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](OC)[C@@H]1OP(=O)([O-])OC[C@H]1O[C@@H](n2cnc3c(=O)[nH]c(N)nc32)[C@H](O)[C@@H]1O

nearest known ligand 0.55

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
P2RY1 P47900 4/20 0.50
P2RY2 P41231 2/20 0.50
SRC P12931 1/20 0.50
P2RX1 P51575 1/20 0.50
P2RX3 P56373 1/20 0.50
P2RX4 Q99571 1/20 0.50
P2RX2 Q9UBL9 1/20 0.50
ALDH1A1 P00352 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
DCPS Q96C86 1/20 0.50
RNASEL Q05823 3/20 0.49
FUT5 Q11128 1/20 0.49
TGM2 P21980 1/20 0.49
KRAS P01116 1/20 0.49
MACROD2 A1Z1Q3 1/20 0.48
SIRT6 Q8N6T7 1/20 0.48
MACROD1 Q9BQ69 1/20 0.48
TRPM2 O94759 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26213758 1.00 P2RY1 (0.50) P2RY1P2RY2SRCP2RX1P2RX3
SCHEMBL26201873 0.97 FUT5 (0.50) P2RY1P2RY2SRCP2RX1P2RX3
SCHEMBL26201802 0.96 P2RY1 (0.51) P2RY1P2RY2SRCP2RX1P2RX3
SCHEMBL26622416 0.96 RNASEL (0.54) P2RY1P2RY2SRCP2RX1P2RX3
SCHEMBL26201976 0.96 DCPS (0.49) P2RY1P2RY2SRCP2RX1P2RX3
SCHEMBL26622375 0.94 P2RY1 (0.53) P2RY1P2RY2SRCP2RX1P2RX3
SCHEMBL26201872 0.94 P2RY2 (0.56) P2RY1P2RY2SRCP2RX1P2RX3
SCHEMBL26584183 0.93 RNASEL (0.53) P2RY1P2RY2SRCP2RX1P2RX3
SCHEMBL26572570 0.93 P2RY1 (0.52) P2RY1P2RY2SRCP2RX1P2RX3
SCHEMBL26213547 0.93 P2RY1 (0.53) P2RY1P2RY2SRCP2RX1P2RX3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230340009-A1 COMPOUNDS FOR RNA CAPPING AND USES THEREOF GUANGZHOU HENOVCOM BIOSCIENCE CO., LTD. (CN) 2023-10-26 US disclosed
WO-2023159930-A1 COMPOUND FOR RNA CAPPING AND APPLICATION OF COMPOUND 广州市恒诺康医药科技有限公司 2023-08-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230340009-A1 COMPOUNDS FOR RNA CAPPING AND USES THEREOF RNGTT, RNMT, NSUN2 P2RY1 4192/4885P2RY2 4360/4885SRC 3673/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.