SCHEMBL26207256

SCHEMBL26207256

C[C@H]1[C@@H](O)[C@H](n2cnc3c(=O)[nH]c(N)nc32)O[C@@H]1COP(=O)(O)O

nearest known ligand 0.74

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ NT5E P21589 1/20 0.74
▸ IMPDH2 P12268 7/20 0.68
▸ IMPDH1 P20839 2/20 0.68
▸ TGM2 P21980 1/20 0.66
▸ TAS1R3 Q7RTX0 2/20 0.65
▸ TAS1R1 Q7RTX1 2/20 0.65
▸ FUT5 Q11128 1/20 0.64
▸ KRAS P01116 6/20 0.62
▸ HINT1 P49773 1/20 0.61
▸ POLB P06746 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22110041 0.93 TGM2 (0.72) NT5EIMPDH2IMPDH1TGM2FUT5
SCHEMBL17371166 0.93 TGM2 (0.72) NT5EIMPDH2IMPDH1TGM2FUT5
SCHEMBL22434694 0.93 NT5E (0.65) NT5EIMPDH2IMPDH1TGM2TAS1R3
E626 SCHEMBL18785103 0.92 NT5E (0.83) NT5EIMPDH2IMPDH1TGM2TAS1R3
E626 SCHEMBL20277596 0.92 NT5E (0.83) NT5EIMPDH2IMPDH1TGM2TAS1R3
E626 SCHEMBL21163348 0.92 NT5E (0.83) NT5EIMPDH2IMPDH1TGM2TAS1R3
E626 SCHEMBL20677331 0.92 NT5E (0.83) NT5EIMPDH2IMPDH1TGM2TAS1R3
E626 SCHEMBL5854 0.92 NT5E (0.83) NT5EIMPDH2IMPDH1TGM2TAS1R3
E626 SCHEMBL21803790 0.92 NT5E (0.83) NT5EIMPDH2IMPDH1TGM2TAS1R3
E626 SCHEMBL165027 0.92 NT5E (0.83) NT5EIMPDH2IMPDH1TGM2TAS1R3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230340009-A1 COMPOUNDS FOR RNA CAPPING AND USES THEREOF GUANGZHOU HENOVCOM BIOSCIENCE CO., LTD. (CN) 2023-10-26 — — US disclosed
WO-2023159930-A1 COMPOUND FOR RNA CAPPING AND APPLICATION OF COMPOUND 广州市恒诺康医药科技有限公司 2023-08-31 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230340009-A1 COMPOUNDS FOR RNA CAPPING AND USES THEREOF RNGTT, RNMT, NSUN2 NT5E 803/4885IMPDH2 881/4885IMPDH1 870/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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