SCHEMBL26211540

SCHEMBL26211540

CNC(=O)CC[C@H]1[C@@H](O)[C@H](n2cnc3c(=O)[nH]c(N)nc32)O[C@@H]1CO

nearest known ligand 0.57

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HINT1 P49773 6/20 0.57
HPGD P15428 2/20 0.53
NT5E P21589 1/20 0.51
GSK3A P49840 2/20 0.51
RPS6KA3 P51812 2/20 0.51
MAPK14 Q16539 2/20 0.51
TGM2 P21980 1/20 0.50
TAAR1 Q96RJ0 1/20 0.50
KRAS P01116 4/20 0.49
PNP P00491 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26208191 0.91 HINT1 (0.57) HINT1HPGDNT5EGSK3ARPS6KA3
SCHEMBL26211537 0.89 HINT1 (0.56) HINT1HPGDNT5EGSK3ARPS6KA3
SCHEMBL26211544 0.88 TAS1R3 (0.61) HINT1NT5ETGM2KRAS
SCHEMBL26622897 0.87 HINT1 (0.61) HINT1HPGDNT5EGSK3ARPS6KA3
SCHEMBL26623531 0.86 HINT1 (0.57) HINT1HPGDNT5EGSK3ARPS6KA3
SCHEMBL20248685 0.86 HPGD (0.64) HINT1HPGDNT5EGSK3ARPS6KA3
SCHEMBL17198349 0.86 HPGD (0.64) HINT1HPGDNT5EGSK3ARPS6KA3
SCHEMBL25711664 0.86 HPGD (0.64) HINT1HPGDNT5EGSK3ARPS6KA3
SCHEMBL26209878 0.85 HINT1 (0.61) HINT1HPGDNT5EGSK3ARPS6KA3
SCHEMBL26207953 0.85 HINT1 (0.58) HINT1HPGDNT5EGSK3ARPS6KA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230340009-A1 COMPOUNDS FOR RNA CAPPING AND USES THEREOF GUANGZHOU HENOVCOM BIOSCIENCE CO., LTD. (CN) 2023-10-26 US disclosed
US-20230340009-A1 COMPOUNDS FOR RNA CAPPING AND USES THEREOF GUANGZHOU HENOVCOM BIOSCIENCE CO., LTD. (CN) 2023-10-26 US disclosed
WO-2023159930-A1 COMPOUND FOR RNA CAPPING AND APPLICATION OF COMPOUND 广州市恒诺康医药科技有限公司 2023-08-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230340009-A1 COMPOUNDS FOR RNA CAPPING AND USES THEREOF RNGTT, RNMT, NSUN2 HINT1 706/4885HPGD 3611/4885NT5E 803/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.