SCHEMBL26211544

SCHEMBL26211544

CNC(=O)CC[C@H]1[C@@H](O)[C@H](n2cnc3c(=O)[nH]c(N)nc32)O[C@@H]1COP(=O)(O)O

nearest known ligand 0.61

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TAS1R3 Q7RTX0 2/20 0.61
TAS1R1 Q7RTX1 2/20 0.61
NT5E P21589 1/20 0.61
TGM2 P21980 1/20 0.59
IMPDH2 P12268 5/20 0.58
IMPDH1 P20839 1/20 0.58
KRAS P01116 9/20 0.58
HINT1 P49773 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26624608 0.94 TGM2 (0.64) TAS1R3TAS1R1NT5ETGM2KRAS
SCHEMBL26208257 0.92 TAS1R3 (0.63) TAS1R3TAS1R1NT5ETGM2IMPDH2
SCHEMBL26622892 0.89 NT5E (0.66) TAS1R3TAS1R1NT5ETGM2IMPDH2
SCHEMBL26624255 0.88 TAS1R3 (0.62) TAS1R3TAS1R1NT5ETGM2IMPDH2
SCHEMBL26623556 0.88 NT5E (0.65) TAS1R3TAS1R1NT5ETGM2IMPDH2
SCHEMBL26207954 0.88 NT5E (0.65) TAS1R3TAS1R1NT5ETGM2IMPDH2
SCHEMBL26208112 0.88 NT5E (0.67) TAS1R3TAS1R1NT5ETGM2IMPDH2
SCHEMBL26211540 0.88 HINT1 (0.57) NT5ETGM2KRASHINT1
SCHEMBL26209245 0.86 NT5E (0.67) TAS1R3TAS1R1NT5ETGM2IMPDH2
SCHEMBL20673346 0.86 NT5E (0.69) TAS1R3TAS1R1NT5ETGM2IMPDH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230340009-A1 COMPOUNDS FOR RNA CAPPING AND USES THEREOF GUANGZHOU HENOVCOM BIOSCIENCE CO., LTD. (CN) 2023-10-26 US disclosed
US-20230340009-A1 COMPOUNDS FOR RNA CAPPING AND USES THEREOF GUANGZHOU HENOVCOM BIOSCIENCE CO., LTD. (CN) 2023-10-26 US disclosed
WO-2023159930-A1 COMPOUND FOR RNA CAPPING AND APPLICATION OF COMPOUND 广州市恒诺康医药科技有限公司 2023-08-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230340009-A1 COMPOUNDS FOR RNA CAPPING AND USES THEREOF RNGTT, RNMT, NSUN2 TAS1R3 3664/4885TAS1R1 3824/4885NT5E 803/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.