SCHEMBL26222268

SCHEMBL26222268

Cc1c(P)c(P)c(P)c(P)c1OC(=O)C(C)C

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ ELANE P08246 2/20 0.36
▸ GAA P10253 1/20 0.33
▸ ALOX15 P16050 1/20 0.31
▸ LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16848728 0.71 TAS1R3 (0.40) ELANEGAAALOX15LMNA
SCHEMBL22381449 0.68 GAA (0.37) ELANEGAAALOX15
SCHEMBL19105005 0.68 TAS1R3 (0.38) ELANEGAAALOX15LMNA
SCHEMBL11915792 0.67 ELANE (0.42) ELANEGAAALOX15
SCHEMBL12299730 0.67 ELANE (0.39) ELANEGAAALOX15
SCHEMBL22381468 0.66 MAPT (0.37) ELANEGAAALOX15
SCHEMBL29027295 0.66 ELANE (0.41) ELANEGAAALOX15
SCHEMBL24394204 0.65 L3MBTL1 (0.62) ELANELMNA
SCHEMBL16788648 0.65 ELANE (0.41) ELANEGAAALOX15
SCHEMBL10509679 0.64 GAA (0.34) ELANEGAALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230295437-A1 SILICON CONTAINING DETECTABLE COMPOUNDS Singular Genomics Systems, Inc. 2023-09-21 — — US disclosed
US-11697736-B2 Silicon containing detectable compounds Singular Genomics Systems, Inc. (US) 2023-07-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11697736-B2 Silicon containing detectable compounds AS3MT, SCLY, NASP ELANE 736/4885GAA 251/4885ALOX15 3974/4885
US-20230295437-A1 SILICON CONTAINING DETECTABLE COMPOUNDS AS3MT, SCLY, NASP ELANE 736/4885GAA 251/4885ALOX15 3974/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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