Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | ELANE | P08246 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10504526 | 0.79 | KDM4E (0.33) | GAALMNATP53MAPT | |
| SCHEMBL10509587 | 0.74 | ALDH1A1 (0.38) | GAALMNATP53MAPT | |
| SCHEMBL10504171 | 0.72 | KDM4E (0.33) | GAALMNATP53MAPT | |
| SCHEMBL10507718 | 0.68 | KMT2A (0.41) | GAALMNATP53MAPT | |
| SCHEMBL16848728 | 0.67 | TAS1R3 (0.40) | GAAELANELMNATP53MAPT | |
| SCHEMBL26144727 | 0.67 | ELANE (0.35) | GAAELANE | |
| SCHEMBL11687811 | 0.65 | GRIN2D (0.32) | LMNA | |
| SCHEMBL10504781 | 0.64 | ABCB11 (0.38) | — | |
| SCHEMBL19105005 | 0.64 | TAS1R3 (0.38) | GAAELANELMNA | |
| SCHEMBL26222268 | 0.64 | ELANE (0.36) | GAAELANELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4871762-A | CARDIOVASCULAR DISORDERS, ANTIALLERGENS | SANKYO COMPANY, LIMITED (JP) | 1989-10-03 | — | — | US | disclosed |