Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | MAP4K3 | Q8IVH8 | 7/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PAICS | P22234 | 1/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
| ▸ | ACVRL1 | P37023 | 4/20 | 0.35 |
| ▸ | ACVR1 | Q04771 | 4/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.34 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.34 |
| ▸ | TLR4 | O00206 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | PLAT | P00750 | 1/20 | 0.33 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL21410769 | 0.98 | KDM1A (0.41) | KDM1AMAP4K3MEN1ALDH1A1MAPT | |
| SCHEMBL174443 | 0.85 | PKM (0.38) | ALDH1A1PKMACVRL1ACVR1BMPR1A | |
| SCHEMBL27843498 | 0.85 | AADAT (0.36) | KDM1AALDH1A1PKMACVR1 | |
| SCHEMBL2077014 | 0.84 | PKM (0.40) | ALDH1A1PKMACVRL1ACVR1BMPR1A | |
| SCHEMBL21410859 | 0.76 | MAP3K7 (0.38) | KDM1A | |
| SCHEMBL22875387 | 0.72 | GPR119 (0.46) | — | |
| SCHEMBL18131219 | 0.70 | MAPT (0.37) | MAP4K3MEN1ALDH1A1MAPTPKM | |
| SCHEMBL22648242 | 0.69 | GABRA1 (0.44) | MAP4K3MEN1ALDH1A1MAPTPKM | |
| SCHEMBL27404589 | 0.69 | CHRNB2 (0.46) | MAP4K3PAK1 | |
| SCHEMBL7883515 | 0.69 | PKM (0.48) | KDM1AMAP4K3MEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11753397-B2 | Cereblon binders for the degradation of ikaros | C4 THERAPEUTICS, INC. (US) | 2023-09-12 | — | — | US | disclosed |
| US-11753397-B2 | Cereblon binders for the degradation of ikaros | C4 THERAPEUTICS, INC. (US) | 2023-09-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11753397-B2 | Cereblon binders for the degradation of ikaros | CRBN, IKZF1, IKZF3 | KDM1A 446/4885MAP4K3 1797/4885MEN1 2469/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.