Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TYMS | P04818 | 4/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | RICTOR | Q6R327 | 1/20 | 0.31 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.31 |
| ▸ | MAPKAP1 | Q9BPZ7 | 1/20 | 0.31 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.31 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.31 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.31 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.31 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.31 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.31 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.31 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26232177 | 0.80 | TYMS (0.41) | KMT2ATYMSGRIA1GRIA2GRIA3 | |
| SCHEMBL17652009 | 0.75 | KMT2A (0.35) | KMT2ATYMSCYP2A6 | |
| SCHEMBL19275108 | 0.71 | XDH (0.38) | XDH | |
| SCHEMBL19275107 | 0.66 | MPO (0.41) | KMT2ATYMS | |
| SCHEMBL18132314 | 0.66 | KMT2A (0.35) | KMT2ACYP2A6 | |
| SCHEMBL13215451 | 0.66 | PDK2 (0.43) | KMT2ACYP2A6 | |
| SCHEMBL19913251 | 0.66 | LRRK2 (0.42) | KMT2A | |
| SCHEMBL28969 | 0.65 | PDPK1 (0.41) | TYMSXDHCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL22788995 | 0.65 | CHUK (0.38) | KMT2ACYP2A6 | |
| SCHEMBL6311633 | 0.65 | CHUK (0.41) | KMT2ACYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11807623-B2 | Nucleic acid-binding photoprobes and uses thereof | ARRAKIS THERAPEUTICS, INC. (US) | 2023-11-07 | — | — | US | disclosed |
| US-20230312520-A1 | NUCLEIC ACID-BINDING PHOTOPROBES AND USES THEREOF | ARRAKIS THERAPEUTICS, INC. | 2023-10-05 | — | — | US | disclosed |
| US-20230286987-A1 | COMPOUNDS | THE PROVOST, FELLOWS, FOUNDATION SCHOLARS, AND THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH, NEAR DUBLIN (IE) | 2023-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230312520-A1 | NUCLEIC ACID-BINDING PHOTOPROBES AND USES THEREOF | NSUN3, NSUN2, TARBP1 | KMT2A 2159/4885TYMS 719/4885XDH 2372/4885 |
| US-20230286987-A1 | COMPOUNDS | HAX1, NHERF1, CXCR1 | KMT2A 512/4885TYMS 4374/4885XDH 61/4885 |
| US-11807623-B2 | Nucleic acid-binding photoprobes and uses thereof | NSUN3, NSUN2, TARBP1 | KMT2A 2159/4885TYMS 719/4885XDH 2372/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.