SCHEMBL26239082

SCHEMBL26239082

CC(C)CNC(=O)C(C)(C)N1CCc2ccccc2C1

nearest known ligand 0.50

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PRMT5 O14744 11/20 0.50
WDR77 Q9BQA1 9/20 0.50
CARM1 Q86X55 1/20 0.44
ACE P12821 1/20 0.44
MAPT P10636 2/20 0.43
TAAR1 Q96RJ0 2/20 0.43
LMNA P02545 1/20 0.43
MMP8 P22894 1/20 0.43
NOTUM Q6P988 1/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
HHAT Q5VTY9 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26238801 0.76 KDM4E (0.46) MAPTLMNAMEN1KMT2A
SCHEMBL26238627 0.75 DRD2 (0.49) MAPTMEN1KMT2A
SCHEMBL25389373 0.73 PRCP (0.48)
SCHEMBL26238804 0.72 MAPT (0.37) MAPTLMNAMEN1KMT2A
SCHEMBL26239089 0.72 OPRL1 (0.46)
SCHEMBL26239085 0.72 ALDH1A1 (0.39) MAPTLMNAMEN1KMT2A
SCHEMBL26238724 0.72 ADRA1A (0.43) MAPTLMNA
SCHEMBL25388967 0.71 SMN1; SMN2 (0.47) MAPTLMNAMEN1KMT2A
SCHEMBL25387883 0.71 MAPT (0.41) MAPTMEN1KMT2A
SCHEMBL26238708 0.70 ALDH1A1 (0.44) MAPTLMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023172415-A1 SWEETENER COMPOSITIONS FIRMENICH INCORPORATED (US) 2023-09-14 WO disclosed