SCHEMBL26239387

SCHEMBL26239387

CCC(C)(CC(C)c1ccc(Cl)cc1)C(=O)O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 4/20 0.40
CYP2C19 P33261 4/20 0.40
MEN1 O00255 4/20 0.40
KMT2A Q03164 4/20 0.40
CYP1A2 P05177 2/20 0.40
CYP3A4 P08684 2/20 0.40
POLB P06746 1/20 0.40
MAPT P10636 1/20 0.40
PPARA Q07869 1/20 0.40
MME P08473 1/20 0.40
ACE P12821 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.39
BRD4 O60885 1/20 0.39
CYP2C9 P11712 6/20 0.38
GABBR2 O75899 3/20 0.38
GABBR1 Q9UBS5 3/20 0.38
LMNA P02545 2/20 0.38
TSHR P16473 2/20 0.38
FFAR2 O15552 1/20 0.38
ADORA3 P0DMS8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26239324 0.92 CYP2C9 (0.46) CYP2D6MEN1KMT2APOLBPPARA
SCHEMBL26239321 0.89 ALDH1A1 (0.47) MEN1KMT2AMAPTCYP2C9LMNA
SCHEMBL26239327 0.87 ACHE (0.46) CYP2D6POLBCYP2C9LMNATSHR
SCHEMBL17721326 0.87 RIPK1 (0.44) CYP2C19MEN1KMT2ACYP3A4FFAR1
SCHEMBL26239320 0.86 HDAC8 (0.41) CYP2D6MEN1KMT2ACYP2C9TSHR
SCHEMBL26239390 0.86 MME (0.39) POLBPPARAMMEACELMNA
SCHEMBL26239316 0.86 GRIA4 (0.47) CYP2D6CYP2C9LMNAFFAR1HIF1A
SCHEMBL26239383 0.86 TSHR (0.36) CYP2D6CYP2C9TSHRFFAR1HIF1A
SCHEMBL26239325 0.86 AKR1C3 (0.41) CYP2C19MAPTL3MBTL1CYP2C9LMNA
SCHEMBL26239386 0.86 FPR2 (0.42) MEN1KMT2ACYP1A2POLBMME

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11754927-B2 Photoresist pattern trimming compositions and pattern formation methods ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2023-09-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11754927-B2 Photoresist pattern trimming compositions and pattern formation methods AHR, ALKBH1, CNOT1 CYP2D6 2178/4885CYP2C19 2610/4885MEN1 4317/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.