Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.60 |
| ▸ | HPGD | P15428 | 4/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.48 |
| ▸ | MME | P08473 | 1/20 | 0.46 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.45 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.45 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26264361 | 0.89 | ALDH1A1 (0.59) | ALDH1A1KDM4EHPGDHSD17B10TDP1 | |
| SCHEMBL12071450 | 0.85 | ALDH1A1 (0.54) | ALDH1A1KDM4EHPGDHSD17B10TDP1 | |
| SCHEMBL26263212 | 0.85 | ALDH1A1 (0.62) | ALDH1A1KDM4EHPGDMAPTRAB9A | |
| SCHEMBL26263209 | 0.83 | SUCNR1 (0.61) | ALDH1A1HPGDSUCNR1 | |
| SCHEMBL26263243 | 0.78 | SUCNR1 (0.68) | ALDH1A1MAPTSUCNR1 | |
| SCHEMBL9756269 | 0.77 | HPGD (0.61) | ALDH1A1HPGDMAPTRAB9ANPC1 | |
| SCHEMBL26263201 | 0.77 | SUCNR1 (0.60) | ALDH1A1KDM4EHPGDMAPTRAB9A | |
| SCHEMBL5842967 | 0.76 | ALDH1A1 (1.00) | ALDH1A1KDM4EHPGDHSD17B10TDP1 | |
| SCHEMBL26263232 | 0.75 | SUCNR1 (0.61) | SUCNR1 | |
| SCHEMBL26263219 | 0.75 | SUCNR1 (0.61) | ALDH1A1KDM4EHPGDSUCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230293504-A1 | TARGETING SUCNR1 TO REDUCE NEUROINFLAMMATION | UNIV NEW YORK (US) | 2023-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230293504-A1 | TARGETING SUCNR1 TO REDUCE NEUROINFLAMMATION | SUCNR1, SYNGR2, TSPO | ALDH1A1 1666/4885KDM4E 3613/4885HPGD 1486/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.