Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.66 |
| ▸ | TMPRSS15 | P98073 | 6/20 | 0.55 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.55 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.51 |
| ▸ | ABL1 | P00519 | 5/20 | 0.50 |
| ▸ | MME | P08473 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGAV | P06756 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | GCGR | P47871 | 1/20 | 0.46 |
| ▸ | MMP12 | P39900 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26263281 | 0.89 | SUCNR1 (0.52) | SUCNR1GPR132ABL1HPGDKDM4E | |
| SCHEMBL26440578 | 0.85 | ALDH1A1 (0.66) | TMPRSS15PRSS1HPGDKDM4EALDH1A1 | |
| SCHEMBL26264447 | 0.83 | KAT6A (0.51) | SUCNR1TMPRSS15PRSS1 | |
| SCHEMBL26264461 | 0.79 | SUCNR1 (1.00) | SUCNR1ABL1 | |
| SCHEMBL3745780 | 0.77 | AURKA (0.67) | ABL1SMN1; SMN2 | |
| SCHEMBL3995770 | 0.77 | FPR2 (0.63) | SUCNR1GPR132MMEITGB3CTSS | |
| SCHEMBL26264367 | 0.76 | SUCNR1 (0.71) | SUCNR1TMPRSS15PRSS1 | |
| SCHEMBL3995775 | 0.76 | MMP12 (0.62) | SUCNR1ALDH1A1ITGB3ITGAVMMP12 | |
| SCHEMBL6609651 | 0.74 | HDAC8 (0.51) | SUCNR1 | |
| SCHEMBL20545896 | 0.74 | CTSA (0.52) | SUCNR1MMESMN1; SMN2MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023183776-A2 | TARGETING SUCNR1 TO REDUCE NEUROINFLAMMATION | NEW YORK UNIVERSITY (US) | 2023-09-28 | — | — | WO | disclosed |
| US-20230293504-A1 | TARGETING SUCNR1 TO REDUCE NEUROINFLAMMATION | UNIV NEW YORK (US) | 2023-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230293504-A1 | TARGETING SUCNR1 TO REDUCE NEUROINFLAMMATION | SUCNR1, SYNGR2, TSPO | SUCNR1 1/4885TMPRSS15 1562/4885PRSS1 1822/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.