Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTMT1 | Q9BV86 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | PYGL | P06737 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26264618 | 1.00 | NTMT1 (0.46) | NTMT1L3MBTL1TDP1ADRA2CPYGL | |
| SCHEMBL26264485 | 0.87 | PPARG (0.45) | L3MBTL1TDP1ADRA2CPYGLLMNA | |
| SCHEMBL26264484 | 0.87 | PPARG (0.45) | L3MBTL1TDP1ADRA2CPYGLLMNA | |
| SCHEMBL26263870 | 0.83 | ANPEP (0.52) | L3MBTL1TDP1LMNAPOLBMEN1 | |
| SCHEMBL25386999 | 0.80 | MTNR1B (0.52) | PYGLLMNAMEN1KMT2ARAB9A | |
| SCHEMBL31595519 | 0.80 | MTNR1B (0.52) | PYGLLMNAMEN1KMT2ARAB9A | |
| SCHEMBL25387001 | 0.80 | MTNR1B (0.52) | PYGLLMNAMEN1KMT2ARAB9A | |
| SCHEMBL30567108 | 0.80 | MTNR1B (0.52) | PYGLLMNAMEN1KMT2ARAB9A | |
| SCHEMBL25386863 | 0.80 | L3MBTL1 (0.55) | L3MBTL1TDP1ADRA2CLMNAPOLB | |
| SCHEMBL31256617 | 0.80 | L3MBTL1 (0.55) | L3MBTL1TDP1ADRA2CLMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023172880-A2 | PCNA INHIBITORS AND USES THEREOF | CITY OF HOPE (US) | 2023-09-14 | — | — | WO | disclosed |