Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | OXTR | P30559 | 1/20 | 0.37 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.37 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26217618 | 0.89 | LMNA (0.41) | LMNASMN1; SMN2NPC1RAB9AGPBAR1 | |
| SCHEMBL26263924 | 0.88 | HCRTR2 (0.37) | LMNAALDH1A1GPBAR1OXTR | |
| SCHEMBL26222016 | 0.81 | ALDH1A1 (0.45) | LMNASMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL26264793 | 0.81 | BCL2A1 (0.46) | LMNAALDH1A1BCL2A1 | |
| SCHEMBL26264797 | 0.81 | LMNA (0.43) | LMNASMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL26264794 | 0.81 | CETP (0.44) | LMNAALDH1A1 | |
| SCHEMBL26264795 | 0.81 | LMNA (0.43) | LMNASMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL26264802 | 0.81 | UTS2R (0.41) | LMNASMN1; SMN2ALDH1A1RAB9AGPBAR1 | |
| SCHEMBL26264792 | 0.81 | LMNA (0.49) | LMNASMN1; SMN2NPC1RAB9ABLM | |
| SCHEMBL26264796 | 0.80 | ALDH1A1 (0.45) | LMNASMN1; SMN2ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230399292-A1 | ANESTHETIC COMPOUNDS AND METHODS OF MAKING AND USING SAME TO TREAT OR PREVENT PAIN SYMPTOMS | PTC Innovations, LLC | 2023-12-14 | — | — | US | disclosed |
| US-11806323-B2 | Topical anesthetics | PTC Innovations, LLC (US) | 2023-11-07 | — | — | US | disclosed |
| US-20230285332-A1 | TOPICAL ANESTHETICS | PTC INNOVATIONS LLC (US) | 2023-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230399292-A1 | ANESTHETIC COMPOUNDS AND METHODS OF MAKING AND USING SAME TO TREAT OR PREVENT PAIN SYMPTOMS | OPRM1, OPRL1, OPRK1 | LMNA 2668/4885SMN1; SMN2 1154/4885ALDH1A1 676/4885 |
| US-20230285332-A1 | TOPICAL ANESTHETICS | OR10J3, ALKBH3, CHRM3 | LMNA 4264/4885SMN1; SMN2 3489/4885ALDH1A1 1175/4885 |
| US-11806323-B2 | Topical anesthetics | OR10J3, ALKBH3, CHRM3 | LMNA 4282/4885SMN1; SMN2 3356/4885ALDH1A1 1212/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.