Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.38 |
| ▸ | OXTR | P30559 | 1/20 | 0.38 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26264804 | 0.89 | LMNA (0.40) | LMNASMN1; SMN2NPC1RAB9AGPBAR1 | |
| SCHEMBL26217412 | 0.81 | BCL2A1 (0.47) | LMNATP53POLBMAPTBCL2A1 | |
| SCHEMBL26217594 | 0.81 | ALDH1A1 (0.46) | LMNASMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL26217450 | 0.80 | LMNA (0.45) | LMNANPC1RAB9ATP53POLB | |
| SCHEMBL26217487 | 0.80 | LMNA (0.45) | LMNASMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL26217430 | 0.80 | CETP (0.43) | LMNATP53POLBMAPT | |
| SCHEMBL26217576 | 0.80 | AHCY (0.42) | LMNASMN1; SMN2RAB9ATP53POLB | |
| SCHEMBL26217384 | 0.80 | LMNA (0.51) | LMNASMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL26217468 | 0.79 | ALDH1A1 (0.47) | LMNASMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL26221117 | 0.79 | POLQ (0.45) | LMNANPC1RAB9ATP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230399292-A1 | ANESTHETIC COMPOUNDS AND METHODS OF MAKING AND USING SAME TO TREAT OR PREVENT PAIN SYMPTOMS | PTC Innovations, LLC | 2023-12-14 | — | — | US | disclosed |
| US-20230399291-A1 | ANESTHETIC COMPOUNDS AND METHODS OF MAKING AND USING SAME TO TREAT OR PREVENT PAIN SYMPTOMS | PTC INNOVATIONS LLC (US) | 2023-12-14 | — | — | US | disclosed |
| US-20230399290-A1 | ANESTHETIC COMPOUNDS AND METHODS OF MAKING AND USING SAME TO TREAT OR PREVENT PAIN SYMPTOMS | PTC INNOVATIONS LLC (US) | 2023-12-14 | — | — | US | disclosed |
| US-20230373906-A1 | ANESTHETIC COMPOUNDS AND METHODS OF MAKING AND USING SAME TO TREAT OR PREVENT PAIN SYMPTOMS | PTC INNOVATIONS LLC (US) | 2023-11-23 | — | — | US | disclosed |
| US-11814335-B1 | Anesthetic compounds and methods of making and using same to treat or prevent pain symptoms | PTC Innovations, LLC (US) | 2023-11-14 | — | — | US | disclosed |
| US-11786493-B2 | Anesthetic compounds and methods of making and using same to treat or prevent pain symptoms | PTC Innovations, LLC (US) | 2023-10-17 | — | — | US | disclosed |
| WO-2023172603-A1 | ANESTHETIC COMPOUNDS AND METHODS OF MAKING AND USING SAME TO TREAT OR PREVENT PAIN SYMPTOMS | PTC Innovations, LLC (US) | 2023-09-14 | — | — | WO | disclosed |
| US-20230286905-A1 | ANESTHETIC COMPOUNDS AND METHODS OF MAKING AND USING SAME TO TREAT OR PREVENT PAIN SYMPTOMS | PTC Innovations, LLC | 2023-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230399290-A1 | ANESTHETIC COMPOUNDS AND METHODS OF MAKING AND USING SAME TO TREAT OR PREVENT PAIN SYMPTOMS | OPRK1, ACHE, F5 | LMNA 2285/4885SMN1; SMN2 1514/4885NPC1 1484/4885 |
| US-20230399292-A1 | ANESTHETIC COMPOUNDS AND METHODS OF MAKING AND USING SAME TO TREAT OR PREVENT PAIN SYMPTOMS | OPRM1, OPRL1, OPRK1 | LMNA 2668/4885SMN1; SMN2 1154/4885NPC1 1723/4885 |
| US-20230399291-A1 | ANESTHETIC COMPOUNDS AND METHODS OF MAKING AND USING SAME TO TREAT OR PREVENT PAIN SYMPTOMS | CHRM2, RXFP2, OPRM1 | LMNA 3130/4885SMN1; SMN2 673/4885NPC1 2618/4885 |
| US-11814335-B1 | Anesthetic compounds and methods of making and using same to treat or prevent pain symptoms | F8, F5, OPRM1 | LMNA 2286/4885SMN1; SMN2 1585/4885NPC1 1543/4885 |
| US-20230286905-A1 | ANESTHETIC COMPOUNDS AND METHODS OF MAKING AND USING SAME TO TREAT OR PREVENT PAIN SYMPTOMS | OPRM1, OPRL1, OPRK1 | LMNA 3532/4885SMN1; SMN2 2140/4885NPC1 966/4885 |
| US-20230373906-A1 | ANESTHETIC COMPOUNDS AND METHODS OF MAKING AND USING SAME TO TREAT OR PREVENT PAIN SYMPTOMS | F5, EIF4G2, ACHE | LMNA 2318/4885SMN1; SMN2 1536/4885NPC1 1414/4885 |
| US-11786493-B2 | Anesthetic compounds and methods of making and using same to treat or prevent pain symptoms | OPRM1, OPRL1, OPRK1 | LMNA 3532/4885SMN1; SMN2 2140/4885NPC1 966/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.