Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.37 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylformamide SCHEMBL28337539 | 0.89 | HTT (0.38) | HTTLMNAHSD17B10CYP2C19CYP2C9 | |
| SCHEMBL3138036 | 0.84 | HTT (0.44) | HTTLMNAHSD17B10CYP2C19CYP2C9 | |
| SCHEMBL29279682 | 0.83 | HTT (0.41) | HTTHSD17B10ALDH1A1POLBHDAC3 | |
| SCHEMBL1492655 | 0.82 | HTT (0.46) | HTTCYP2C19CYP2C9TSHRCYP1A2 | |
| SCHEMBL25816145 | 0.81 | CYP1A2 (0.57) | HTTHSD17B10CYP2C19CYP2C9TSHR | |
| SCHEMBL9157016 | 0.81 | PIN1 (0.46) | HTTCYP2C19CYP2C9TSHRPOLB | |
| SCHEMBL4062734 | 0.79 | LMNA (0.41) | LMNAHSD17B10CYP2C19TSHRCYP1A2 | |
| SCHEMBL4071095 | 0.79 | TSHR (0.57) | LMNAHSD17B10TSHRCYP1A2AKR1C3 | |
| SCHEMBL6773227 | 0.79 | TSHR (0.57) | LMNAHSD17B10TSHRCYP1A2AKR1C3 | |
| SCHEMBL1928791 | 0.79 | ACP3 (0.43) | LMNAHSD17B10CYP2C19CYP2C9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118768579-A | Preparation method and application of monodisperse silver nanoparticles | 丽水学院 | 2024-10-15 | — | — | CN | claimed |
| CN-101380317-B | Pharmaceutical composition for relieving pruritus | CAYMAN ISLAND SHANGANSHENG DEV PHARMACEUTICAL CO LTD | 2010-12-08 | — | — | CN | claimed |
| EP-2033635-A1 | Short-chain fatty acid derivatives for treating pruritus | Asan Laboratories Company (Cayman) Limited (CN) | 2009-03-11 | — | — | EP | claimed |
| CN-101380317-A | Pharmaceutical composition for relieving pruritus | CAYMAN ISLAND SHANGANSHENG DEV (CN) | 2009-03-11 | — | — | CN | claimed |
| US-20080107646-A1 | Administering phenylbutyric acid derivative and pharmaceutically acceptable carrier | Sunny Pharmtech Inc. (TW) | 2008-05-08 | — | — | US | claimed |
| US-6403646-B1 | ADMINISTERING PHENYLBUTYRIC ACID OR DERIVATIVES TO TREAT LIVER DISEASE AND EMPHYSEMA CAUSED BY PROTEASE INHIBITOR TYPE Z MUTATION; STIMULATES SECRETION WITHOUT INCREASING SYNTHESIS OF PROTEIN | PERLMUTTER DAVID H (US) | 2002-06-11 | — | — | US | claimed |
| US-12404295-B2 | (Hetero)aryl-methyl-thio-beta-D-galactopyranoside derivatives | IDORSIA PHARMACEUTICALS LTD (CH) | 2025-09-02 | — | — | US | disclosed |
| CN-118768579-A | Preparation method and application of monodisperse silver nanoparticles | 丽水学院 | 2024-10-15 | — | — | CN | disclosed |
| EP-4010076-B1 | (HETERO)ARYL-METHYL-THIO-BETA-D-GALACTOPYRANOSIDE DERIVATIVES | IDORSIA PHARMACEUTICALS LTD (CH) | 2024-01-17 | — | — | EP | disclosed |
| US-20220315619-A1 | (HETERO)ARYL-METHYL-THIO-BETA-D-GALACTOPYRANOSIDE DERIVATIVES | IDORSIA PHARMACEUTICALS LTD (CH) | 2022-10-06 | — | — | US | disclosed |
| CN-114702630-A | Lignin-based polymer and preparation method and application thereof | 中国林业科学研究院林产化学工业研究所 | 2022-07-05 | — | — | CN | disclosed |
| CN-111777540-B | Method for synthesizing pyrrolidone compound by continuous light-induced catalysis | 南京工业大学 | 2021-09-24 | — | — | CN | disclosed |
| CN-111777540-A | Method for synthesizing pyrrolidone compound by continuous light-induced catalysis | 南京工业大学 | 2020-10-16 | — | — | CN | disclosed |
| EP-0353248-A1 | METHOD FOR RESOLUTION OF STEREOISOMERS IN MULTIPHASE AND EXTRACTIVE MEMBRANE REACTORS. | SEPRACOR INC (US) | 1990-02-07 | — | — | EP | disclosed |
| US-4800162-A | ENZYME-ACTIVATED MEMBRANE | SEPRACOR, INC. (US) | 1989-01-24 | — | — | US | disclosed |
| WO-1988007582-A1 | METHOD FOR RESOLUTION OF STEREOISOMERS IN MULTIPHASE AND EXTRACTIVE MEMBRANE REACTORS | SEPRACOR, INC. (US) | 1988-10-06 | — | — | WO | disclosed |
| US-4288453-A | A-(1-PHENYL-2,2,2-TRIFLUOROETHOXY (OR -ETHYLTHIO))ALKANOIC ACIDS USEFUL AS ANTICHOLESTEROL AND ANTILIPEMIC AGENTS | SCIENCE UNION ET CIE (FR) | 1981-09-08 | — | — | US | disclosed |
| US-4118393-A | Phenyl azabicyclohexanones | AMERICAN CYANAMID COMPANY (US) | 1978-10-03 | — | — | US | disclosed |
| US-4001233-A | CNS STIMULANTS, MUSCLE RELAXANTS | E. R. SQUIBB & SONS, INC. (US) | 1977-01-04 | — | — | US | disclosed |
| US-3957787-A | CENTRAL NERVOUS SYSTEM STIMULANTS, MUSCLE RELAXANTS | E. R. SQUIBB & SONS, INC. (US) | 1976-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220315619-A1 | (HETERO)ARYL-METHYL-THIO-BETA-D-GALACTOPYRANOSIDE DERIVATIVES | LGALS1, LGALS3, LGALS2 | HTT 1755/4885LMNA 1963/4885HSD17B10 2291/4885 |
| US-12404295-B2 | (Hetero)aryl-methyl-thio-beta-D-galactopyranoside derivatives | LGALS1, LGALS3, LGALS2 | HTT 1755/4885LMNA 1963/4885HSD17B10 2291/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.