Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 10/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.76 |
| ▸ | MAPT | P10636 | 3/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.76 |
| ▸ | MEN1 | O00255 | 2/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.76 |
| ▸ | AHR | P35869 | 1/20 | 0.73 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.63 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 6/20 | 0.60 |
| ▸ | TP53 | P04637 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | CTSV | O60911 | 1/20 | 0.59 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.59 |
| ▸ | TUBB | P07437 | 1/20 | 0.59 |
| ▸ | CTSL | P07711 | 1/20 | 0.59 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18084362 | 0.89 | HPGD (0.61) | HPGDALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL1071573 | 0.89 | IMPDH2 (0.61) | HPGDALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL31552893 | 0.87 | ALDH1A1 (1.00) | HPGDALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL1273190 | 0.85 | HPGD (0.57) | HPGDALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL2630603 | 0.84 | HPGD (0.76) | HPGDALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL341241 | 0.81 | CTSV (0.62) | HPGDALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL31439158 | 0.81 | ALDH1A1 (0.72) | HPGDALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL6534282 | 0.81 | HPGD (1.00) | HPGDALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL6534320 | 0.81 | HPGD (0.79) | HPGDALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL339864 | 0.80 | HPGD (0.78) | HPGDALDH1A1KDM4EMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116377457-A | Electrochemical synthesis method of halogenated quinoline-4 (1H) -ketone derivative | 桂林理工大学 | 2023-07-04 | — | — | CN | disclosed |