SCHEMBL2630693

SCHEMBL2630693

CCC(C)(C=O)CC(C)C=O

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.37
TSHR P16473 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28545841 0.83
SCHEMBL15333490 0.79
SCHEMBL14048307 0.77
SCHEMBL20996792 0.77
SCHEMBL14022084 0.77 FDPS (0.34)
SCHEMBL15266380 0.77 TP53 (0.34) TP53TSHR
SCHEMBL5364973 0.76 TP53 (0.35) TP53TSHR
SCHEMBL270156 0.74
SCHEMBL26625981 0.73 TP53 (0.41) TP53TSHR
SCHEMBL14034844 0.73 TP53 (0.37) TP53TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120263789-A1 DELAYED RELEASE RASAGILINE FORMULATION TEVA PHARMACEUTICAL INDUSTRIES LTD. 2012-10-18 US disclosed
US-20120100189-A1 DELAYED RELEASE RASAGILINE MALATE FORMULATION TEVA PHARMACEUTICAL INDUSTRIES LTD. 2012-04-26 US disclosed
US-20120003310-A1 DELAYED RELEASE RASAGILINE FORMULATION TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) 2012-01-05 US disclosed
US-20100189791-A1 Delayed release rasagiline malate formulation TEVA PHARMACEUTICAL INDUSTRIES, LTD. 2010-07-29 US disclosed
US-20100189788-A1 Delayed release rasagiline base formulation TEVA PHARMACEUTICAL INDUSTRIES, LTD. 2010-07-29 US disclosed
US-20090181086-A1 Rasagiline formulations, their preparation and use TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) 2009-07-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120100189-A1 DELAYED RELEASE RASAGILINE MALATE FORMULATION MDH1, MDH2, SLC25A11 TP53 3603/4885TSHR 4315/4885
US-20120003310-A1 DELAYED RELEASE RASAGILINE FORMULATION RAB7A, RAB5B, RAB27A TP53 3320/4885TSHR 2264/4885
US-20100189788-A1 Delayed release rasagiline base formulation RAB7A, RAB27A, RAB5B TP53 4460/4885TSHR 2402/4885
US-20090181086-A1 Rasagiline formulations, their preparation and use RAB5B, RAB27A, RAB29 TP53 4093/4885TSHR 3463/4885
US-20100189791-A1 Delayed release rasagiline malate formulation MDH1, MDH2, SLC25A11 TP53 3603/4885TSHR 4315/4885
US-20120263789-A1 DELAYED RELEASE RASAGILINE FORMULATION RAB7A, RAB27A, RAB35 TP53 4277/4885TSHR 2050/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.