Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.50 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | EED | O75530 | 1/20 | 0.38 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.36 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.36 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.35 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.35 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29523159 | 1.00 | ABCG2 (0.50) | ABCG2AOC3HTR2AHTR2CGSK3B | |
| SCHEMBL31452716 | 0.83 | ABCG2 (0.41) | ABCG2AOC3HTR2AHTR2CPKM | |
| SCHEMBL4564550 | 0.82 | ITGB2 (0.50) | MAPK1KDM4EALDH1A1LMNAHTR1A | |
| SCHEMBL38654029 | 0.78 | ITGB2 (0.41) | MAOBKDM4EALDH1A1LMNA | |
| SCHEMBL31454272 | 0.78 | ABCG2 (0.31) | ABCG2HTR2AHTR2CHTR1A | |
| SCHEMBL30583926 | 0.78 | ABCG2 (0.31) | ABCG2HTR2AHTR2CHTR1A | |
| SCHEMBL7594061 | 0.76 | ABCG2 (0.55) | ABCG2GSK3BPKMTSHREED | |
| SCHEMBL30521296 | 0.74 | ABCG2 (0.52) | ABCG2GSK3BPKMTSHREED | |
| SCHEMBL1224045 | 0.74 | ABCG2 (0.52) | ABCG2GSK3BPKMTSHREED | |
| SCHEMBL2168952 | 0.74 | EED (0.46) | ABCG2AOC3HTR2AHTR2CGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 180 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106749204-A | A kind of preparation method of piribedil | 郑州大明药物科技有限公司 | 2017-05-31 | — | — | CN | claimed |
| US-20080249128-A1 | Substituted Sulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2008-10-09 | — | — | US | claimed |
| CN-122036680-A | Anti-fibrotic pyridones | 英特穆恩公司 | 2026-05-15 | — | — | CN | disclosed |
| EP-4317162-B1 | 1,3-BENZODIOXOLANE-CONTAINING COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | XIAN XINTONG PHARMACEUTICAL RES CO LTD (CN) | 2026-02-04 | — | — | EP | disclosed |
| US-20260022096-A1 | NOVEL SULFONAMIDES AND THEIR USE AS NEUROPROTECTIVE AND/OR NEURORESTORATIVE AGENTS | GENECODE (EE) | 2026-01-22 | — | — | US | disclosed |
| US-12435060-B2 | Acylamino bridged heterocyclic compound, and composition and application thereof | BEIJING SCITECH-MQ PHARMACEUTICALS LIMITED (CN) | 2025-10-07 | — | — | US | disclosed |
| US-20250296915-A1 | NOVEL AMINO ACID DERIVATIVES | PEPTIDREAM INC (JP) | 2025-09-25 | — | — | US | disclosed |
| US-20250179046-A1 | SEROTONIN 5-HT2B INHIBITORY COMPOUNDS | ZOETIS SERVICES LLC | 2025-06-05 | — | — | US | disclosed |
| EP-4561994-A1 | NOVEL SULFONAMIDES AND THEIR USE AS NEUROPROTECTIVE AND/OR NEURORESTORATIVE AGENTS | Genecode (EE) | 2025-06-04 | — | — | EP | disclosed |
| US-12240827-B2 | Serotonin 5-HT2B inhibitory compounds | ZOETIS SERVICES LLC (US) | 2025-03-04 | — | — | US | disclosed |
| US-20250026766-A1 | Thiazolopyridyl Amide Derivatives as DNA Polymerase Theta Inhibitors | BEIGENE, LTD. (KY) | 2025-01-23 | — | — | US | disclosed |
| US-4978801-A | Preparation of aromatic aldehydes | RHONE-POULENC CHIMIE (FR) | 1990-12-18 | — | — | US | disclosed |
| US-4942240-A | REACTION OF HYDROGEN AND CARBON MONOXIDE WITH AN AROMATIC HALIDE IN THE PRESENCE OF A NOBLE METAL CATALYSTS | RHONE-POULENC CHIMIE (FR) | 1990-07-17 | — | — | US | disclosed |
| US-4746358-A | PLANT GROWTH REGULATORS, HERBICIDES; N-TRIAZINYL-AMINOCARBONYL -1,4-BENZODIOXANESULFONAMIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-05-24 | — | — | US | disclosed |
| EP-0244328-A2 | Process for the preparation of aromatic aldehydes | RHONE-POULENC CHIMIE (FR) | 1987-11-04 | — | — | EP | disclosed |
| EP-0244329-A2 | Process for the preparation of aromatic aldehydes | RHONE-POULENC CHIMIE (FR) | 1987-11-04 | — | — | EP | disclosed |
| US-4659368-A | HERBICIDES; PLANT GROWTH REGULATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-04-21 | — | — | US | disclosed |
| US-4595407-A | Triazinyl-amino-carbonyl-1,3-benzohetero- or -1,4-benzohetero-sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-06-17 | — | — | US | disclosed |
| US-4502882-A | HERBICIDES, PLANT GROWTH REGULATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-03-05 | — | — | US | disclosed |
| EP-0082681-A2 | Herbicidal sulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-06-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12240827-B2 | Serotonin 5-HT2B inhibitory compounds | HTR2B, HTR1B, HTR5A | ABCG2 273/4885AOC3 2550/4885HTR2A 9/4885 |
| US-20250179046-A1 | SEROTONIN 5-HT2B INHIBITORY COMPOUNDS | HTR2B, HTR1B, HTR5A | ABCG2 273/4885AOC3 2550/4885HTR2A 9/4885 |
| US-20250296915-A1 | NOVEL AMINO ACID DERIVATIVES | DNPEP, BCAT1, ANPEP | ABCG2 842/4885AOC3 4644/4885HTR2A 3126/4885 |
| US-20260022096-A1 | NOVEL SULFONAMIDES AND THEIR USE AS NEUROPROTECTIVE AND/OR NEURORESTORATIVE AGENTS | CNR1, CDR2, SMN1; SMN2 | ABCG2 684/4885AOC3 768/4885HTR2A 1496/4885 |
| US-20080249128-A1 | Substituted Sulfonamide Compounds | BDKRB1, BDKRB2, NPSR1 | ABCG2 350/4885AOC3 3678/4885HTR2A 464/4885 |
| US-20250026766-A1 | Thiazolopyridyl Amide Derivatives as DNA Polymerase Theta Inhibitors | POLQ, POLK, POLI | ABCG2 3423/4885AOC3 3492/4885HTR2A 4540/4885 |
| US-12435060-B2 | Acylamino bridged heterocyclic compound, and composition and application thereof | RIPK1, RIPK3, RIPK4 | ABCG2 1665/4885AOC3 4463/4885HTR2A 4631/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.