Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4057007 | 0.92 | MEN1 (0.54) | ALDH1A1LMNAKMT2AMEN1L3MBTL1 | |
| SCHEMBL4049726 | 0.81 | MAPT (0.52) | ALDH1A1LMNAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL4049720 | 0.81 | MAPT (0.52) | ALDH1A1LMNAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL3653439 | 0.81 | MEN1 (0.65) | ALDH1A1LMNAKMT2AMEN1L3MBTL1 | |
| SCHEMBL26313592 | 0.78 | ALDH1A1 (0.58) | ALDH1A1LMNAKMT2AMEN1L3MBTL1 | |
| SCHEMBL4059272 | 0.77 | ALDH1A1 (0.63) | ALDH1A1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL7021479 | 0.77 | SMN1; SMN2 (0.64) | ALDH1A1LMNAKMT2AMEN1L3MBTL1 | |
| SCHEMBL14574205 | 0.77 | LMNA (0.50) | ALDH1A1LMNAKMT2APOLBSMN1; SMN2 | |
| SCHEMBL14938228 | 0.77 | TAAR1 (0.47) | ALDH1A1LMNAKMT2ASMN1; SMN2RAB9A | |
| SCHEMBL18767163 | 0.77 | ALDH1A1 (0.52) | ALDH1A1LMNAKMT2AMEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009111260-A1 | PHENYLSULFONAMIDE-SUBSTITUTED, PYRAZOLO[1, 5-A]PYRIMIDINES, METHODS FOR PREPARATION AND USES THEREOF | WYETH (US) | 2009-09-11 | — | — | WO | disclosed |