Flopropione

Flopropione

SCHEMBL26316

CCC(=O)c1c(O)cc(O)cc1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 6/20 1.00
MEN1 O00255 4/20 1.00
KMT2A Q03164 4/20 1.00
PTGS1 P23219 1/20 1.00
DRD3 P35462 1/20 1.00
HPGD P15428 3/20 0.56
HSP90AB1 P08238 1/20 0.55
NR1H2 P55055 1/20 0.55
NR1H3 Q13133 1/20 0.55
SLC5A1 P13866 5/20 0.50
SLC5A2 P31639 5/20 0.50
MAPT P10636 3/20 0.50
TDP1 Q9NUW8 2/20 0.50
GAA P10253 2/20 0.50
MAPK1 P28482 2/20 0.50
CYP19A1 P11511 2/20 0.50
KDM4E B2RXH2 1/20 0.50
SLC16A3 O15427 1/20 0.50
ALDH1A1 P00352 1/20 0.50
LMNA P02545 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15676364 0.87 CYP3A4 (0.77) CYP3A4MEN1KMT2APTGS1DRD3
SCHEMBL1500125 0.86 CYP3A4 (0.74) CYP3A4MEN1KMT2APTGS1DRD3
SCHEMBL15372539 0.82 CYP3A4 (0.69) CYP3A4MEN1KMT2APTGS1DRD3
SCHEMBL2788789 0.82 MEN1 (0.69) CYP3A4MEN1KMT2APTGS1DRD3
SCHEMBL28312119 0.82 MEN1 (0.69) CYP3A4MEN1KMT2APTGS1DRD3
Hydrochloric Acid SCHEMBL28825358 0.80 MEN1 (0.67) CYP3A4MEN1KMT2APTGS1DRD3
SCHEMBL7550984 0.80 CYP3A4 (0.67) CYP3A4MEN1KMT2APTGS1DRD3
SCHEMBL7300081 0.79 MEN1 (0.65) CYP3A4MEN1KMT2APTGS1DRD3
SCHEMBL28155500 0.79 CYP3A4 (0.65) CYP3A4MEN1KMT2APTGS1DRD3
SCHEMBL2790900 0.79 MEN1 (0.64) CYP3A4MEN1KMT2APTGS1DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 938 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250295611-A1 METHODS OF TREATING 5HT2A RECEPTOR-MEDIATED CONDITIONS TESSELLATE THERAPEUTICS INC (US) 2025-09-25 US claimed
US-20250090501-A1 METHODS OF TREATING GUT MOTILITY DISORDERS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-03-20 US claimed
US-20250009655-A1 BIPHASIC COMPOSITIONS COMPRISING ONE OR BOTH OF CARBONATE AND PHOSPHATE Natural Extraction Systems, LLC 2025-01-09 US claimed
EP-4460293-A2 METHODS OF TREATING GUT MOTILITY DISORDERS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-11-13 EP claimed
US-20240315965-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2024-09-26 US claimed
WO-2023212244-A1 METHODS OF TREATING 5HT2A RECEPTOR-MEDIATED CONDITIONS TESSELLATE THERAPEUTICS, INC. (US) 2023-11-02 WO claimed
US-20230346879-A1 COMPOSITIONS AND METHODS FOR COMBINATORIAL DRUG DISCOVERY IN NANOLITER DROPLETS MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2023-11-02 US claimed
US-11794009-B2 Devices, systems and methods for treating urological and gastrointestinal disorders by electrical stimulation of the foot University of Pittsburgh—of the Commonwealth System of Higher Education (US) 2023-10-24 US claimed
WO-2023130149-A2 METHODS OF TREATING GUT MOTILITY DISORDERS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-07-06 WO claimed
WO-2023064318-A1 BIPHASIC COMPOSITIONS COMPRISING ONE OR BOTH OF CARBONATE AND PHOSPHATE Natural Extraction Systems, LLC (US) 2023-04-20 WO claimed
US-20060074108-A1 Matrix metalloprotease (MMP) inhibitors and their application in cosmetic and pharmaceutical composition BIODERM RESEARCH (US) 2006-04-06 US claimed
CN-1730455-A Phloroglucinol propionyl derivative and synthetic method thereof and application BIOLOGY INST OF SHANDONG ACADE (CN) 2006-02-08 CN claimed
US-20050271608-A1 Skin whitening compositions based on hydroxyaryl alkyl ketones and their isosteric derivatives GUPTA SHYAM K 2005-12-08 US claimed
WO-2005035473-A2 METHOD FOR PREPARING LADDERANES FROM PRE-ORIENTED POLYENES UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 2005-04-21 WO claimed
CN-1294519-A Pharmaceutical composition containing a compound having an activity of promoting the absorption of an active ingredient INPHARMA SA (CH) 2001-05-09 CN claimed
EP-1073470-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2001-02-07 EP claimed
WO-2000048636-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2000-08-24 WO claimed
US-5811547-A Method for inducing crystalline state transition in medicinal substance NIPPON SHINYAJU CO., LTD. (JP) 1998-09-22 US claimed
EP-0046270-B1 NOVEL DERIVATIVES OF BIO-AFFECTING PHENOLIC COMPOUNDS AND PHARMACEUTICAL COMPOSITION CONTAINING THEM INTERx RESEARCH CORPORATION (US) 1986-05-21 EP claimed
EP-0046270-A1 Novel derivatives of bio-affecting phenolic compounds and pharmaceutical composition containing them INTERx RESEARCH CORPORATION (US) 1982-02-24 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230346879-A1 COMPOSITIONS AND METHODS FOR COMBINATORIAL DRUG DISCOVERY IN NANOLITER DROPLETS RAB5IF, CLTB, TBK1 CYP3A4 4180/4885MEN1 4717/4885KMT2A 4648/4885
US-20250090501-A1 METHODS OF TREATING GUT MOTILITY DISORDERS SI, SLC10A2, FABP2 CYP3A4 1408/4885MEN1 3229/4885KMT2A 3191/4885
US-20250295611-A1 METHODS OF TREATING 5HT2A RECEPTOR-MEDIATED CONDITIONS HTR2A, HTR5A, HTR6 CYP3A4 1995/4885MEN1 2593/4885KMT2A 1760/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.