Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.51 |
| ▸ | KDM1A | O60341 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | JAK1 | P23458 | 4/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.47 |
| ▸ | CKS1B | P61024 | 1/20 | 0.47 |
| ▸ | SKP1 | P63208 | 1/20 | 0.47 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30531972 | 1.00 | DRD2 (0.51) | DRD2KDM1AMAOBKMT2AL3MBTL1 | |
| SCHEMBL4627783 | 0.79 | KDM1A (0.52) | DRD2KDM1AMAOBKMT2AL3MBTL1 | |
| SCHEMBL4814305 | 0.79 | KDM1A (0.52) | DRD2KDM1AMAOBKMT2AL3MBTL1 | |
| SCHEMBL3865823 | 0.78 | KDM1A (0.52) | DRD2KDM1AMAOBKMT2AL3MBTL1 | |
| SCHEMBL14334645 | 0.78 | GPR119 (0.59) | NAMPT | |
| SCHEMBL17830852 | 0.76 | CKS1B (0.61) | DRD2KDM1AMAOBKMT2AL3MBTL1 | |
| SCHEMBL13999223 | 0.76 | KDM1A (0.58) | DRD2KDM1AMAOBKMT2AL3MBTL1 | |
| SCHEMBL30201369 | 0.75 | KMT2A (0.61) | DRD2KDM1AMAOBKMT2AL3MBTL1 | |
| SCHEMBL12794285 | 0.75 | CTSK (0.52) | DRD2KDM1AMAOBKMT2AL3MBTL1 | |
| SCHEMBL12794288 | 0.75 | CTSK (0.52) | DRD2KDM1AMAOBKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023152349-A1 | IRAK4 INHIBITORS | ASTRAZENECA AB (SE) | 2023-08-17 | — | — | WO | disclosed |