Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26319663 | 0.83 | HCAR3 (0.34) | MAPK1FDPS | |
| SCHEMBL13127917 | 0.80 | HTT (0.46) | FFAR2MAPK1HTTLMNAALDH1A1 | |
| SCHEMBL1225938 | 0.80 | MEN1 (0.42) | FFAR2MAPK1HTTLMNAALDH1A1 | |
| SCHEMBL1225937 | 0.80 | MEN1 (0.42) | FFAR2MAPK1HTTLMNAALDH1A1 | |
| SCHEMBL26319671 | 0.78 | MAPK1 (0.41) | FFAR2MAPK1HTTLMNAALDH1A1 | |
| SCHEMBL19243702 | 0.77 | ALDH1A1 (0.45) | FFAR2MAPK1HTTLMNAALDH1A1 | |
| Isaxonine SCHEMBL2846192 | 0.74 | MAPK1 (0.48) | FFAR2MAPK1HTTLMNAALDH1A1 | |
| Isaxonine SCHEMBL1270289 | 0.74 | KCNH3 (0.43) | MAPK1HTTLMNAALDH1A1MEN1 | |
| Isaxonine SCHEMBL4537710 | 0.72 | FDPS (0.42) | FFAR2MAPK1HTTLMNANPC1 | |
| Isaxonine SCHEMBL9030532 | 0.72 | PKM (0.40) | FFAR2MAPK1HTTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023164057-A1 | DI-CYCLOPROPYL BASED IL-17A MODULATORS AND USES THEREOF | DICE ALPHA, INC. (US) | 2023-08-31 | — | — | WO | disclosed |