Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B10 | O60218 | 7/20 | 0.61 |
| ▸ | AKR1B1 | P15121 | 7/20 | 0.61 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.57 |
| ▸ | TTR | P02766 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.47 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.47 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.47 |
| ▸ | MET | P08581 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20915000 | 0.88 | AKR1B10 (0.67) | AKR1B10AKR1B1ALOX5TTRKDM4E | |
| SCHEMBL30449449 | 0.88 | AKR1B10 (0.67) | AKR1B10AKR1B1ALOX5TTRKDM4E | |
| SCHEMBL20914978 | 0.81 | AKR1B10 (0.66) | AKR1B10AKR1B1ALOX5TTRKDM4E | |
| SCHEMBL30610039 | 0.81 | AKR1B10 (0.66) | AKR1B10AKR1B1ALOX5TTRKDM4E | |
| SCHEMBL9641020 | 0.80 | ALOX5 (0.67) | AKR1B10AKR1B1ALOX5TTRKDM4E | |
| SCHEMBL9641906 | 0.80 | ALOX5 (0.67) | AKR1B10AKR1B1ALOX5TTRKDM4E | |
| SCHEMBL20914959 | 0.79 | ALOX5 (0.70) | AKR1B10AKR1B1ALOX5TTRKDM4E | |
| SCHEMBL22577476 | 0.78 | ALOX5 (0.85) | AKR1B10AKR1B1ALOX5TTRKDM4E | |
| SCHEMBL355844 | 0.76 | HCAR2 (0.72) | AKR1B10AKR1B1ALOX5TTRKDM4E | |
| SCHEMBL8708780 | 0.76 | HCAR2 (0.72) | AKR1B10AKR1B1ALOX5TTRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11760715-B2 | Modulators of lipoxygenase and cyclooxygenase enzyme activity | UNIVERSITÉ DE MONCTON (CA) | 2023-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11760715-B2 | Modulators of lipoxygenase and cyclooxygenase enzyme activity | ALOX12, ALOX15B, ALOX5 | AKR1B10 392/4885AKR1B1 182/4885ALOX5 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.